Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit

Lack of correct embryo transport can cause ectopic pregnancy. Here, the authors show that female mice lacking the adhesion G-protein coupled receptor Adgrd1 are infertile, due to embryos being trapped in the ampulla as the result of dysregulated oviductal fluid flow.

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Autores principales:	Enrica Bianchi, Yi Sun, Alexandra Almansa-Ordonez, Michael Woods, David Goulding, Nadia Martinez-Martin, Gavin J. Wright
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/22fbc19c7d8d408483697d387763d42a
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spelling	oai:doaj.org-article:22fbc19c7d8d408483697d387763d42a2021-12-02T10:59:14ZControl of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit10.1038/s41467-021-21512-w2041-1723https://doaj.org/article/22fbc19c7d8d408483697d387763d42a2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21512-whttps://doaj.org/toc/2041-1723Lack of correct embryo transport can cause ectopic pregnancy. Here, the authors show that female mice lacking the adhesion G-protein coupled receptor Adgrd1 are infertile, due to embryos being trapped in the ampulla as the result of dysregulated oviductal fluid flow.Enrica BianchiYi SunAlexandra Almansa-OrdonezMichael WoodsDavid GouldingNadia Martinez-MartinGavin J. WrightNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Enrica Bianchi Yi Sun Alexandra Almansa-Ordonez Michael Woods David Goulding Nadia Martinez-Martin Gavin J. Wright Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
description	Lack of correct embryo transport can cause ectopic pregnancy. Here, the authors show that female mice lacking the adhesion G-protein coupled receptor Adgrd1 are infertile, due to embryos being trapped in the ampulla as the result of dysregulated oviductal fluid flow.
format	article
author	Enrica Bianchi Yi Sun Alexandra Almansa-Ordonez Michael Woods David Goulding Nadia Martinez-Martin Gavin J. Wright
author_facet	Enrica Bianchi Yi Sun Alexandra Almansa-Ordonez Michael Woods David Goulding Nadia Martinez-Martin Gavin J. Wright
author_sort	Enrica Bianchi
title	Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
title_short	Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
title_full	Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
title_fullStr	Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
title_full_unstemmed	Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
title_sort	control of oviductal fluid flow by the g-protein coupled receptor adgrd1 is essential for murine embryo transit
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/22fbc19c7d8d408483697d387763d42a
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Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit

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