Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit

Lack of correct embryo transport can cause ectopic pregnancy. Here, the authors show that female mice lacking the adhesion G-protein coupled receptor Adgrd1 are infertile, due to embryos being trapped in the ampulla as the result of dysregulated oviductal fluid flow.

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Auteurs principaux: Enrica Bianchi, Yi Sun, Alexandra Almansa-Ordonez, Michael Woods, David Goulding, Nadia Martinez-Martin, Gavin J. Wright
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/22fbc19c7d8d408483697d387763d42a
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