IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL

Experimental autoimmune encephalomyelitis in an adoptive transfer model is caused by injecting animal with activated T cells specific for a CNS antigen, e.g., basic myelin protein. Development of autimmune inflammation in such a model is connected with changed functional stateof encephalytogenic (EG...

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Autores principales: M. A. Nosov, E. A. Korneva
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Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/2302584ecffc4e10b1bab6644e526f4c
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spelling oai:doaj.org-article:2302584ecffc4e10b1bab6644e526f4c2021-11-18T08:03:41ZIN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL1563-06252313-741X10.15789/1563-0625-2010-6-565-568https://doaj.org/article/2302584ecffc4e10b1bab6644e526f4c2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/476https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XExperimental autoimmune encephalomyelitis in an adoptive transfer model is caused by injecting animal with activated T cells specific for a CNS antigen, e.g., basic myelin protein. Development of autimmune inflammation in such a model is connected with changed functional stateof encephalytogenic (EG) T cells in the coure of disease progression, as reflected by changes in their activation, proliferation and motility levels. Present work describes an original technique allowing for in vitro analysis of encephalytogenic T cell motility, and studying effects of certain compomemts of extracellular matrix upon migration and functional activities of EG T cells.M. A. NosovE. A. KornevaSPb RAACIarticleexperimental autoimmune encephalomyelitisencephalytogenic t cellsmigrationextracellular matrixImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 6, Pp 565-568 (2014)
institution DOAJ
collection DOAJ
language RU
topic experimental autoimmune encephalomyelitis
encephalytogenic t cells
migration
extracellular matrix
Immunologic diseases. Allergy
RC581-607
spellingShingle experimental autoimmune encephalomyelitis
encephalytogenic t cells
migration
extracellular matrix
Immunologic diseases. Allergy
RC581-607
M. A. Nosov
E. A. Korneva
IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
description Experimental autoimmune encephalomyelitis in an adoptive transfer model is caused by injecting animal with activated T cells specific for a CNS antigen, e.g., basic myelin protein. Development of autimmune inflammation in such a model is connected with changed functional stateof encephalytogenic (EG) T cells in the coure of disease progression, as reflected by changes in their activation, proliferation and motility levels. Present work describes an original technique allowing for in vitro analysis of encephalytogenic T cell motility, and studying effects of certain compomemts of extracellular matrix upon migration and functional activities of EG T cells.
format article
author M. A. Nosov
E. A. Korneva
author_facet M. A. Nosov
E. A. Korneva
author_sort M. A. Nosov
title IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
title_short IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
title_full IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
title_fullStr IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
title_full_unstemmed IN VITRO ANALYSIS OF MIGRATION ACTIVITY OF ENCEPHALYTOGENIC T CEL
title_sort in vitro analysis of migration activity of encephalytogenic t cel
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/2302584ecffc4e10b1bab6644e526f4c
work_keys_str_mv AT manosov invitroanalysisofmigrationactivityofencephalytogenictcel
AT eakorneva invitroanalysisofmigrationactivityofencephalytogenictcel
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