Counterregulation of cAMP-directed kinase activities controls ciliogenesis

The mechanisms that control ciliogenesis have been extensively explored however the signaling mechanisms that control cilium stability remain unclear. Here the authors show that GPCR signaling regulates cilia resorption via the ubiquitin-proteasome system.

Guardado en:

Detalles Bibliográficos
Autores principales:	Monia Porpora, Simona Sauchella, Laura Rinaldi, Rossella Delle Donne, Maria Sepe, Omar Torres-Quesada, Daniela Intartaglia, Corrado Garbi, Luigi Insabato, Margherita Santoriello, Verena A. Bachmann, Matthis Synofzik, Herbert H. Lindner, Ivan Conte, Eduard Stefan, Antonio Feliciello
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23040612179646c4bd606c5eb5df82fa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:23040612179646c4bd606c5eb5df82fa
record_format	dspace
spelling	oai:doaj.org-article:23040612179646c4bd606c5eb5df82fa2021-12-02T16:56:39ZCounterregulation of cAMP-directed kinase activities controls ciliogenesis10.1038/s41467-018-03643-92041-1723https://doaj.org/article/23040612179646c4bd606c5eb5df82fa2018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03643-9https://doaj.org/toc/2041-1723The mechanisms that control ciliogenesis have been extensively explored however the signaling mechanisms that control cilium stability remain unclear. Here the authors show that GPCR signaling regulates cilia resorption via the ubiquitin-proteasome system.Monia PorporaSimona SauchellaLaura RinaldiRossella Delle DonneMaria SepeOmar Torres-QuesadaDaniela IntartagliaCorrado GarbiLuigi InsabatoMargherita SantorielloVerena A. BachmannMatthis SynofzikHerbert H. LindnerIvan ConteEduard StefanAntonio FelicielloNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Monia Porpora Simona Sauchella Laura Rinaldi Rossella Delle Donne Maria Sepe Omar Torres-Quesada Daniela Intartaglia Corrado Garbi Luigi Insabato Margherita Santoriello Verena A. Bachmann Matthis Synofzik Herbert H. Lindner Ivan Conte Eduard Stefan Antonio Feliciello Counterregulation of cAMP-directed kinase activities controls ciliogenesis
description	The mechanisms that control ciliogenesis have been extensively explored however the signaling mechanisms that control cilium stability remain unclear. Here the authors show that GPCR signaling regulates cilia resorption via the ubiquitin-proteasome system.
format	article
author	Monia Porpora Simona Sauchella Laura Rinaldi Rossella Delle Donne Maria Sepe Omar Torres-Quesada Daniela Intartaglia Corrado Garbi Luigi Insabato Margherita Santoriello Verena A. Bachmann Matthis Synofzik Herbert H. Lindner Ivan Conte Eduard Stefan Antonio Feliciello
author_facet	Monia Porpora Simona Sauchella Laura Rinaldi Rossella Delle Donne Maria Sepe Omar Torres-Quesada Daniela Intartaglia Corrado Garbi Luigi Insabato Margherita Santoriello Verena A. Bachmann Matthis Synofzik Herbert H. Lindner Ivan Conte Eduard Stefan Antonio Feliciello
author_sort	Monia Porpora
title	Counterregulation of cAMP-directed kinase activities controls ciliogenesis
title_short	Counterregulation of cAMP-directed kinase activities controls ciliogenesis
title_full	Counterregulation of cAMP-directed kinase activities controls ciliogenesis
title_fullStr	Counterregulation of cAMP-directed kinase activities controls ciliogenesis
title_full_unstemmed	Counterregulation of cAMP-directed kinase activities controls ciliogenesis
title_sort	counterregulation of camp-directed kinase activities controls ciliogenesis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/23040612179646c4bd606c5eb5df82fa
work_keys_str_mv	AT moniaporpora counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT simonasauchella counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT laurarinaldi counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT rosselladelledonne counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT mariasepe counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT omartorresquesada counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT danielaintartaglia counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT corradogarbi counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT luigiinsabato counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT margheritasantoriello counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT verenaabachmann counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT matthissynofzik counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT herberthlindner counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT ivanconte counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT eduardstefan counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis AT antoniofeliciello counterregulationofcampdirectedkinaseactivitiescontrolsciliogenesis
_version_	1718382730115284992

Counterregulation of cAMP-directed kinase activities controls ciliogenesis

Ejemplares similares