Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle

Ruslan Deviatiiarov et al. identify torpor-specific promoters with an enriched binding motif and the transcription factor ATF3 highly expressed during torpor deprivation. Knocking out Atf3 affected the torpor phenotype, giving rise to molecular targets for studying and translating hypometabolic stat...

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Autores principales:	Ruslan Deviatiiarov, Kiyomi Ishikawa, Guzel Gazizova, Takaya Abe, Hiroshi Kiyonari, Masayo Takahashi, Oleg Gusev, Genshiro A. Sunagawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/23055b9e5cd1406fb42ff08eff6788f5
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spelling	oai:doaj.org-article:23055b9e5cd1406fb42ff08eff6788f52021-11-21T12:08:19ZIntegrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle10.1038/s42003-021-02819-22399-3642https://doaj.org/article/23055b9e5cd1406fb42ff08eff6788f52021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02819-2https://doaj.org/toc/2399-3642Ruslan Deviatiiarov et al. identify torpor-specific promoters with an enriched binding motif and the transcription factor ATF3 highly expressed during torpor deprivation. Knocking out Atf3 affected the torpor phenotype, giving rise to molecular targets for studying and translating hypometabolic states.Ruslan DeviatiiarovKiyomi IshikawaGuzel GazizovaTakaya AbeHiroshi KiyonariMasayo TakahashiOleg GusevGenshiro A. SunagawaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Ruslan Deviatiiarov Kiyomi Ishikawa Guzel Gazizova Takaya Abe Hiroshi Kiyonari Masayo Takahashi Oleg Gusev Genshiro A. Sunagawa Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
description	Ruslan Deviatiiarov et al. identify torpor-specific promoters with an enriched binding motif and the transcription factor ATF3 highly expressed during torpor deprivation. Knocking out Atf3 affected the torpor phenotype, giving rise to molecular targets for studying and translating hypometabolic states.
format	article
author	Ruslan Deviatiiarov Kiyomi Ishikawa Guzel Gazizova Takaya Abe Hiroshi Kiyonari Masayo Takahashi Oleg Gusev Genshiro A. Sunagawa
author_facet	Ruslan Deviatiiarov Kiyomi Ishikawa Guzel Gazizova Takaya Abe Hiroshi Kiyonari Masayo Takahashi Oleg Gusev Genshiro A. Sunagawa
author_sort	Ruslan Deviatiiarov
title	Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
title_short	Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
title_full	Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
title_fullStr	Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
title_full_unstemmed	Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
title_sort	integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/23055b9e5cd1406fb42ff08eff6788f5
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Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle

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