Integrative transcription start site analysis and physiological phenotyping reveal torpor-specific expression program in mouse skeletal muscle

Ruslan Deviatiiarov et al. identify torpor-specific promoters with an enriched binding motif and the transcription factor ATF3 highly expressed during torpor deprivation. Knocking out Atf3 affected the torpor phenotype, giving rise to molecular targets for studying and translating hypometabolic stat...

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Autores principales: Ruslan Deviatiiarov, Kiyomi Ishikawa, Guzel Gazizova, Takaya Abe, Hiroshi Kiyonari, Masayo Takahashi, Oleg Gusev, Genshiro A. Sunagawa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/23055b9e5cd1406fb42ff08eff6788f5
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