Genome sequence of the pea aphid Acyrthosiphon pisum.

Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first pu...

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Autor principal:	International Aphid Genomics Consortium
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/2307c1d097294cfda07c6eac9fdbc7a1
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spelling	oai:doaj.org-article:2307c1d097294cfda07c6eac9fdbc7a12021-12-02T19:54:28ZGenome sequence of the pea aphid Acyrthosiphon pisum.1544-91731545-788510.1371/journal.pbio.1000313https://doaj.org/article/2307c1d097294cfda07c6eac9fdbc7a12010-02-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20186266/pdf/?tool=EBIhttps://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.International Aphid Genomics ConsortiumPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 8, Iss 2, p e1000313 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 International Aphid Genomics Consortium Genome sequence of the pea aphid Acyrthosiphon pisum.
description	Aphids are important agricultural pests and also biological models for studies of insect-plant interactions, symbiosis, virus vectoring, and the developmental causes of extreme phenotypic plasticity. Here we present the 464 Mb draft genome assembly of the pea aphid Acyrthosiphon pisum. This first published whole genome sequence of a basal hemimetabolous insect provides an outgroup to the multiple published genomes of holometabolous insects. Pea aphids are host-plant specialists, they can reproduce both sexually and asexually, and they have coevolved with an obligate bacterial symbiont. Here we highlight findings from whole genome analysis that may be related to these unusual biological features. These findings include discovery of extensive gene duplication in more than 2000 gene families as well as loss of evolutionarily conserved genes. Gene family expansions relative to other published genomes include genes involved in chromatin modification, miRNA synthesis, and sugar transport. Gene losses include genes central to the IMD immune pathway, selenoprotein utilization, purine salvage, and the entire urea cycle. The pea aphid genome reveals that only a limited number of genes have been acquired from bacteria; thus the reduced gene count of Buchnera does not reflect gene transfer to the host genome. The inventory of metabolic genes in the pea aphid genome suggests that there is extensive metabolite exchange between the aphid and Buchnera, including sharing of amino acid biosynthesis between the aphid and Buchnera. The pea aphid genome provides a foundation for post-genomic studies of fundamental biological questions and applied agricultural problems.
format	article
author	International Aphid Genomics Consortium
author_facet	International Aphid Genomics Consortium
author_sort	International Aphid Genomics Consortium
title	Genome sequence of the pea aphid Acyrthosiphon pisum.
title_short	Genome sequence of the pea aphid Acyrthosiphon pisum.
title_full	Genome sequence of the pea aphid Acyrthosiphon pisum.
title_fullStr	Genome sequence of the pea aphid Acyrthosiphon pisum.
title_full_unstemmed	Genome sequence of the pea aphid Acyrthosiphon pisum.
title_sort	genome sequence of the pea aphid acyrthosiphon pisum.
publisher	Public Library of Science (PLoS)
publishDate	2010
url	https://doaj.org/article/2307c1d097294cfda07c6eac9fdbc7a1
work_keys_str_mv	AT internationalaphidgenomicsconsortium genomesequenceofthepeaaphidacyrthosiphonpisum
_version_	1718375888985260032

Genome sequence of the pea aphid Acyrthosiphon pisum.

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