High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis

Jae-Beom Lee,1 Yun-Seok Choi,2 Woo-Baek Chung,2 Ami Kwon,2 Chul-Soo Park,2 Man-Young Lee2 1Anyang Sam Hospital, 2Division of Cardiology, Department of Internal Medicine, Youido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Purpose: High coronary...

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Autores principales:	Lee JB, Choi YS, Chung WB, Kwon AM, Park CS, Lee MY
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Coronary restenosis drug-eluting stents calcium Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/2308459f1d9d446e9c6525400678e989
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spelling	oai:doaj.org-article:2308459f1d9d446e9c6525400678e9892021-12-02T07:59:33ZHigh coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis1178-1998https://doaj.org/article/2308459f1d9d446e9c6525400678e9892017-02-01T00:00:00Zhttps://www.dovepress.com/high-coronary-calcium-score-and-post-procedural-ck-mb-are-noninvasive--peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Jae-Beom Lee,1 Yun-Seok Choi,2 Woo-Baek Chung,2 Ami Kwon,2 Chul-Soo Park,2 Man-Young Lee2 1Anyang Sam Hospital, 2Division of Cardiology, Department of Internal Medicine, Youido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Purpose: High coronary calcium score (CCS) and post-procedural cardiac enzyme may be related with poor outcomes in patients with coronary stent implantation. Methods: A total of 1,072 patients (63.2% male, mean age: 61.7±10.3 years) who underwent coronary multi-detect computed tomography at index procedure and follow-up coronary angiography (CAG) after drug-eluting stent (DES) were divided into two groups: those with and without target lesion revascularization (TLR; >50% reduction in luminal stent diameter or angina symptoms on follow-up CAG). The CCSs for predicting stent revascularization were elucidated. Results: There were no significant differences between the two groups with regard to risk factors. The initial CCS was significantly higher in the TLR group (1,102.4±743.7 vs 345.8±51.05, P=0.04). After adjustment of significant factors for TLR, only CCS and post-procedural creatine kinase MB form (CK-MB) elevation were significant predictors of coronary artery TLR. Receiver operation curve revealed that >800 in CCS had 69% in sensitivity and 88% in specificity about predicting the TLR. Conclusion: High CCS with post-procedural CK-MB might be the useful predictors for TLR after DES implantation. Keywords: coronary restenosis, drug-eluting stents, calcium, creatine kinaseLee JBChoi YSChung WBKwon AMPark CSLee MYDove Medical PressarticleCoronary restenosisdrug-eluting stentscalciumGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 399-404 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Coronary restenosis drug-eluting stents calcium Geriatrics RC952-954.6
spellingShingle	Coronary restenosis drug-eluting stents calcium Geriatrics RC952-954.6 Lee JB Choi YS Chung WB Kwon AM Park CS Lee MY High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
description	Jae-Beom Lee,1 Yun-Seok Choi,2 Woo-Baek Chung,2 Ami Kwon,2 Chul-Soo Park,2 Man-Young Lee2 1Anyang Sam Hospital, 2Division of Cardiology, Department of Internal Medicine, Youido St Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Purpose: High coronary calcium score (CCS) and post-procedural cardiac enzyme may be related with poor outcomes in patients with coronary stent implantation. Methods: A total of 1,072 patients (63.2% male, mean age: 61.7±10.3 years) who underwent coronary multi-detect computed tomography at index procedure and follow-up coronary angiography (CAG) after drug-eluting stent (DES) were divided into two groups: those with and without target lesion revascularization (TLR; >50% reduction in luminal stent diameter or angina symptoms on follow-up CAG). The CCSs for predicting stent revascularization were elucidated. Results: There were no significant differences between the two groups with regard to risk factors. The initial CCS was significantly higher in the TLR group (1,102.4±743.7 vs 345.8±51.05, P=0.04). After adjustment of significant factors for TLR, only CCS and post-procedural creatine kinase MB form (CK-MB) elevation were significant predictors of coronary artery TLR. Receiver operation curve revealed that >800 in CCS had 69% in sensitivity and 88% in specificity about predicting the TLR. Conclusion: High CCS with post-procedural CK-MB might be the useful predictors for TLR after DES implantation. Keywords: coronary restenosis, drug-eluting stents, calcium, creatine kinase
format	article
author	Lee JB Choi YS Chung WB Kwon AM Park CS Lee MY
author_facet	Lee JB Choi YS Chung WB Kwon AM Park CS Lee MY
author_sort	Lee JB
title	High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
title_short	High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
title_full	High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
title_fullStr	High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
title_full_unstemmed	High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis
title_sort	high coronary calcium score and post-procedural ck-mb are noninvasive predictors of coronary stent restenosis
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/2308459f1d9d446e9c6525400678e989
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High coronary calcium score and post-procedural CK-MB are noninvasive predictors of coronary stent restenosis

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