Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents
Background: The relationship between obesity, arterial hypertension, and excessive salt intake has been known for a long time; however, the mechanism of this relationship remains not clear. Methods: The paper presents a current literature review on the relationship between salt consumption and the d...
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2021
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oai:doaj.org-article:2312a6fa307e4bfbaa50268d2e5c0ade2021-11-25T18:36:15ZObesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents10.3390/nu131140322072-6643https://doaj.org/article/2312a6fa307e4bfbaa50268d2e5c0ade2021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/4032https://doaj.org/toc/2072-6643Background: The relationship between obesity, arterial hypertension, and excessive salt intake has been known for a long time; however, the mechanism of this relationship remains not clear. Methods: The paper presents a current literature review on the relationship between salt consumption and the development of arterial hypertension in children and adolescents with obesity. Results: In addition to the traditional theory of hypertension development due to the increase in intravascular volume and disturbances of sodium excretion, recent studies indicate the existence of a complex mechanism related to excessive, pathological secretory activity of adipocytes, insulin resistance, and impaired function of the renin–angiotensin–aldosterone axis. That makes obese children and adolescents particularly vulnerable to the development of salt-sensitive arterial hypertension. Studies performed in many countries have shown that children and adolescents consume more sodium than recommended. It is worth noting, however, that the basis for these recommendations was the extrapolation of data from studies conducted on adults. Moreover, more important than sodium intake is the Na/K ratio and water consumption. Conclusion: Regardless of the population-wide recommendations on reducing salt intake in children, specific recommendations for overweight and obese patients should be developed.Małgorzata WójcikAgnieszka Kozioł-KozakowskaMDPI AGarticleobesityhypertensionsaltsodiumchildrenNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 4032, p 4032 (2021) |
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obesity hypertension salt sodium children Nutrition. Foods and food supply TX341-641 |
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obesity hypertension salt sodium children Nutrition. Foods and food supply TX341-641 Małgorzata Wójcik Agnieszka Kozioł-Kozakowska Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents |
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Background: The relationship between obesity, arterial hypertension, and excessive salt intake has been known for a long time; however, the mechanism of this relationship remains not clear. Methods: The paper presents a current literature review on the relationship between salt consumption and the development of arterial hypertension in children and adolescents with obesity. Results: In addition to the traditional theory of hypertension development due to the increase in intravascular volume and disturbances of sodium excretion, recent studies indicate the existence of a complex mechanism related to excessive, pathological secretory activity of adipocytes, insulin resistance, and impaired function of the renin–angiotensin–aldosterone axis. That makes obese children and adolescents particularly vulnerable to the development of salt-sensitive arterial hypertension. Studies performed in many countries have shown that children and adolescents consume more sodium than recommended. It is worth noting, however, that the basis for these recommendations was the extrapolation of data from studies conducted on adults. Moreover, more important than sodium intake is the Na/K ratio and water consumption. Conclusion: Regardless of the population-wide recommendations on reducing salt intake in children, specific recommendations for overweight and obese patients should be developed. |
format |
article |
author |
Małgorzata Wójcik Agnieszka Kozioł-Kozakowska |
author_facet |
Małgorzata Wójcik Agnieszka Kozioł-Kozakowska |
author_sort |
Małgorzata Wójcik |
title |
Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents |
title_short |
Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents |
title_full |
Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents |
title_fullStr |
Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents |
title_full_unstemmed |
Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents |
title_sort |
obesity, sodium homeostasis, and arterial hypertension in children and adolescents |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/2312a6fa307e4bfbaa50268d2e5c0ade |
work_keys_str_mv |
AT małgorzatawojcik obesitysodiumhomeostasisandarterialhypertensioninchildrenandadolescents AT agnieszkakoziołkozakowska obesitysodiumhomeostasisandarterialhypertensioninchildrenandadolescents |
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1718410880792657920 |