Understanding the genetic determinants of the brain with MOSTest

Understanding the genetic determinants of the brain with MOSTest

Regional brain morphology has a complex genetic architecture. Here the authors present MOSTest, a multivariate statistical framework, apply it to UK Biobank data, and discover hundreds of loci associated with regional brain morphology.

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Detalles Bibliográficos
Autores principales: Dennis van der Meer, Oleksandr Frei, Tobias Kaufmann, Alexey A. Shadrin, Anna Devor, Olav B. Smeland, Wesley K. Thompson, Chun Chieh Fan, Dominic Holland, Lars T. Westlye, Ole A. Andreassen, Anders M. Dale
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/23142a35894143158339487e31feb0c1
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Descripción
Sumario:Regional brain morphology has a complex genetic architecture. Here the authors present MOSTest, a multivariate statistical framework, apply it to UK Biobank data, and discover hundreds of loci associated with regional brain morphology.

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