Improvement of a predictive model of castration-resistant prostate cancer: functional genetic variants in TGFβ1 signaling pathway modulation.

Improvement of a predictive model of castration-resistant prostate cancer: functional genetic variants in TGFβ1 signaling pathway modulation.

Prostate cancer (PC) is the most frequently diagnosed cancer in men. The acquisition of castration-resistant (CR) phenotype is associated with the activation of signaling pathways mediated by growth factors. The TGFβ1 and its receptors have an important role in tumor progression, being the pro-apopt...

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Autores principales: Ana L Teixeira, Mónica Gomes, Augusto Nogueira, Andreia S Azevedo, Joana Assis, Francisca Dias, Juliana I Santos, Francisco Lobo, António Morais, Joaquina Maurício, Rui Medeiros
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2320ca9fc7ed448495322603bfef8f0d
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