Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)

BACKGROUND AND OBJECTIVE: Very low birth weight (VLBW) infants (4-7% live birth) are at high risk for mortality (one third of neonatal mortality). To determine the frequency of disease-free survival, complications and risk factors for morbidity and mortality in VLBW neonates. METHODS: This cross-sec...

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Autores principales:	SA Afjeh, MK Sabzehei, M Fallahi, F Esmaili
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2012
Materias:	neonatal mortality very low birth weight infant risk factors Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/2323051f892d425b9d57c6ca69698d82
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spelling	oai:doaj.org-article:2323051f892d425b9d57c6ca69698d822021-11-10T08:53:33ZSurvival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)1561-41072251-7170https://doaj.org/article/2323051f892d425b9d57c6ca69698d822012-11-01T00:00:00Zhttp://jbums.org/article-1-4227-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Very low birth weight (VLBW) infants (4-7% live birth) are at high risk for mortality (one third of neonatal mortality). To determine the frequency of disease-free survival, complications and risk factors for morbidity and mortality in VLBW neonates. METHODS: This cross-sectional retrospective study was performed from April 2007 to March 2010 on all hospitalized VLBW neonates in neonatal intensive care unit (NICU) at the Mahdieh hospital in Tehran, Iran. Relevant pre- and peri-natal data up to the time of discharge from the hospital or death, including complications during the course of hospitalization, were collected and compared.FINDINGS: Five hundred and sixty four neonates were included in the study during three years. Overall survival was 70.9% in ELBW newborns this figure was 33.3% rising to 84.1% in infants weighing between 1001-1500 grams. Mean gestational age was 29.6 ± 2.5 weeks, mean birth weight was 1179 ± 258 grams and Mean hospitalization duration was 29.7 ± 23.6. Mean birth weight, gestational age and APGAR scores were significantly higher in babies who survived than those who died, (1275 ± 189 vs. 944 ± 253 grams 30.5 ± 2.2 vs. 27.5 ± 2 weeks and 6.9 ± 1.7 vs. 5 ± 2.1 respectively p <0.001 in all instances) but needs for CPR was more in dead newborns (p<0.001). Need for mechanical ventilation, pulmonary hemorrhage and gastro-intestinal bleeding were also significant predictive factors for mortality.CONCLUSION: Although our survival was compatible with most of developing countries but for improving survival, especially in ELBW suggest increasing the quality of prenatal care, regionalization, standard CPR in delivery room and improving the quality of care in NICU.SA AfjehMK Sabzehei,M FallahiF EsmailiBabol University of Medical Sciencesarticleneonatal mortalityvery low birth weight infantrisk factorsMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 14, Iss 6, Pp 7-16 (2012)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	neonatal mortality very low birth weight infant risk factors Medicine R Medicine (General) R5-920
spellingShingle	neonatal mortality very low birth weight infant risk factors Medicine R Medicine (General) R5-920 SA Afjeh MK Sabzehei, M Fallahi F Esmaili Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)
description	BACKGROUND AND OBJECTIVE: Very low birth weight (VLBW) infants (4-7% live birth) are at high risk for mortality (one third of neonatal mortality). To determine the frequency of disease-free survival, complications and risk factors for morbidity and mortality in VLBW neonates. METHODS: This cross-sectional retrospective study was performed from April 2007 to March 2010 on all hospitalized VLBW neonates in neonatal intensive care unit (NICU) at the Mahdieh hospital in Tehran, Iran. Relevant pre- and peri-natal data up to the time of discharge from the hospital or death, including complications during the course of hospitalization, were collected and compared.FINDINGS: Five hundred and sixty four neonates were included in the study during three years. Overall survival was 70.9% in ELBW newborns this figure was 33.3% rising to 84.1% in infants weighing between 1001-1500 grams. Mean gestational age was 29.6 ± 2.5 weeks, mean birth weight was 1179 ± 258 grams and Mean hospitalization duration was 29.7 ± 23.6. Mean birth weight, gestational age and APGAR scores were significantly higher in babies who survived than those who died, (1275 ± 189 vs. 944 ± 253 grams 30.5 ± 2.2 vs. 27.5 ± 2 weeks and 6.9 ± 1.7 vs. 5 ± 2.1 respectively p <0.001 in all instances) but needs for CPR was more in dead newborns (p<0.001). Need for mechanical ventilation, pulmonary hemorrhage and gastro-intestinal bleeding were also significant predictive factors for mortality.CONCLUSION: Although our survival was compatible with most of developing countries but for improving survival, especially in ELBW suggest increasing the quality of prenatal care, regionalization, standard CPR in delivery room and improving the quality of care in NICU.
format	article
author	SA Afjeh MK Sabzehei, M Fallahi F Esmaili
author_facet	SA Afjeh MK Sabzehei, M Fallahi F Esmaili
author_sort	SA Afjeh
title	Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)
title_short	Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)
title_full	Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)
title_fullStr	Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)
title_full_unstemmed	Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)
title_sort	survival of very low birth weight infants in neonatal intensive care unit at the mahdieh hospital (tehran-iran)
publisher	Babol University of Medical Sciences
publishDate	2012
url	https://doaj.org/article/2323051f892d425b9d57c6ca69698d82
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Survival of Very Low Birth Weight Infants in Neonatal Intensive Care Unit at the Mahdieh Hospital (Tehran-Iran)

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