Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis

Chemo-enzymatic tandem processes allow access to more complex non-racemic products. Here, the authors show that non-ionic surfactants, especially the tailor-made surfactant TPGS-750-M, enhance the activity of alcohol dehydrogenase to afford stereopure products in a 1-pot reaction.

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Detalles Bibliográficos
Autores principales: Margery Cortes-Clerget, Nnamdi Akporji, Jianguang Zhou, Feng Gao, Pengfei Guo, Michael Parmentier, Fabrice Gallou, Jean-Yves Berthon, Bruce H. Lipshutz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2324756d621441b68c4e51ade06bad80
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Sumario:Chemo-enzymatic tandem processes allow access to more complex non-racemic products. Here, the authors show that non-ionic surfactants, especially the tailor-made surfactant TPGS-750-M, enhance the activity of alcohol dehydrogenase to afford stereopure products in a 1-pot reaction.