Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis

Chemo-enzymatic tandem processes allow access to more complex non-racemic products. Here, the authors show that non-ionic surfactants, especially the tailor-made surfactant TPGS-750-M, enhance the activity of alcohol dehydrogenase to afford stereopure products in a 1-pot reaction.

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Autores principales: Margery Cortes-Clerget, Nnamdi Akporji, Jianguang Zhou, Feng Gao, Pengfei Guo, Michael Parmentier, Fabrice Gallou, Jean-Yves Berthon, Bruce H. Lipshutz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2324756d621441b68c4e51ade06bad80
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spelling oai:doaj.org-article:2324756d621441b68c4e51ade06bad802021-12-02T17:02:03ZBridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis10.1038/s41467-019-09751-42041-1723https://doaj.org/article/2324756d621441b68c4e51ade06bad802019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09751-4https://doaj.org/toc/2041-1723Chemo-enzymatic tandem processes allow access to more complex non-racemic products. Here, the authors show that non-ionic surfactants, especially the tailor-made surfactant TPGS-750-M, enhance the activity of alcohol dehydrogenase to afford stereopure products in a 1-pot reaction.Margery Cortes-ClergetNnamdi AkporjiJianguang ZhouFeng GaoPengfei GuoMichael ParmentierFabrice GallouJean-Yves BerthonBruce H. LipshutzNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Margery Cortes-Clerget
Nnamdi Akporji
Jianguang Zhou
Feng Gao
Pengfei Guo
Michael Parmentier
Fabrice Gallou
Jean-Yves Berthon
Bruce H. Lipshutz
Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
description Chemo-enzymatic tandem processes allow access to more complex non-racemic products. Here, the authors show that non-ionic surfactants, especially the tailor-made surfactant TPGS-750-M, enhance the activity of alcohol dehydrogenase to afford stereopure products in a 1-pot reaction.
format article
author Margery Cortes-Clerget
Nnamdi Akporji
Jianguang Zhou
Feng Gao
Pengfei Guo
Michael Parmentier
Fabrice Gallou
Jean-Yves Berthon
Bruce H. Lipshutz
author_facet Margery Cortes-Clerget
Nnamdi Akporji
Jianguang Zhou
Feng Gao
Pengfei Guo
Michael Parmentier
Fabrice Gallou
Jean-Yves Berthon
Bruce H. Lipshutz
author_sort Margery Cortes-Clerget
title Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
title_short Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
title_full Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
title_fullStr Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
title_full_unstemmed Bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
title_sort bridging the gap between transition metal- and bio-catalysis via aqueous micellar catalysis
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2324756d621441b68c4e51ade06bad80
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AT nnamdiakporji bridgingthegapbetweentransitionmetalandbiocatalysisviaaqueousmicellarcatalysis
AT jianguangzhou bridgingthegapbetweentransitionmetalandbiocatalysisviaaqueousmicellarcatalysis
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AT jeanyvesberthon bridgingthegapbetweentransitionmetalandbiocatalysisviaaqueousmicellarcatalysis
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