Auto-FPFA: An Automated Microscope for Characterizing Genetically Encoded Biosensors

Abstract Genetically encoded biosensors function by linking structural change in a protein construct, typically tagged with one or more fluorescent proteins, to changes in a biological parameter of interest (such as calcium concentration, pH, phosphorylation-state, etc.). Typically, the structural c...

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Autores principales: Tuan A. Nguyen, Henry L. Puhl, An K. Pham, Steven S. Vogel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2325b19a934c460e9d076cd0bad58623
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