Interspecies conservation of organisation and function between nonhomologous regional centromeres

Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conse...

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Autores principales: Pin Tong, Alison L. Pidoux, Nicholas R. T. Toda, Ryan Ard, Harald Berger, Manu Shukla, Jesus Torres-Garcia, Carolin A. Müller, Conrad A. Nieduszynski, Robin C. Allshire
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/2326eb1cb7ff4d129bd2996e9215ca50
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spelling oai:doaj.org-article:2326eb1cb7ff4d129bd2996e9215ca502021-12-02T17:33:23ZInterspecies conservation of organisation and function between nonhomologous regional centromeres10.1038/s41467-019-09824-42041-1723https://doaj.org/article/2326eb1cb7ff4d129bd2996e9215ca502019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09824-4https://doaj.org/toc/2041-1723Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin.Pin TongAlison L. PidouxNicholas R. T. TodaRyan ArdHarald BergerManu ShuklaJesus Torres-GarciaCarolin A. MüllerConrad A. NieduszynskiRobin C. AllshireNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pin Tong
Alison L. Pidoux
Nicholas R. T. Toda
Ryan Ard
Harald Berger
Manu Shukla
Jesus Torres-Garcia
Carolin A. Müller
Conrad A. Nieduszynski
Robin C. Allshire
Interspecies conservation of organisation and function between nonhomologous regional centromeres
description Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin.
format article
author Pin Tong
Alison L. Pidoux
Nicholas R. T. Toda
Ryan Ard
Harald Berger
Manu Shukla
Jesus Torres-Garcia
Carolin A. Müller
Conrad A. Nieduszynski
Robin C. Allshire
author_facet Pin Tong
Alison L. Pidoux
Nicholas R. T. Toda
Ryan Ard
Harald Berger
Manu Shukla
Jesus Torres-Garcia
Carolin A. Müller
Conrad A. Nieduszynski
Robin C. Allshire
author_sort Pin Tong
title Interspecies conservation of organisation and function between nonhomologous regional centromeres
title_short Interspecies conservation of organisation and function between nonhomologous regional centromeres
title_full Interspecies conservation of organisation and function between nonhomologous regional centromeres
title_fullStr Interspecies conservation of organisation and function between nonhomologous regional centromeres
title_full_unstemmed Interspecies conservation of organisation and function between nonhomologous regional centromeres
title_sort interspecies conservation of organisation and function between nonhomologous regional centromeres
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/2326eb1cb7ff4d129bd2996e9215ca50
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