Interspecies conservation of organisation and function between nonhomologous regional centromeres
Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conse...
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2019
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oai:doaj.org-article:2326eb1cb7ff4d129bd2996e9215ca502021-12-02T17:33:23ZInterspecies conservation of organisation and function between nonhomologous regional centromeres10.1038/s41467-019-09824-42041-1723https://doaj.org/article/2326eb1cb7ff4d129bd2996e9215ca502019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09824-4https://doaj.org/toc/2041-1723Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin.Pin TongAlison L. PidouxNicholas R. T. TodaRyan ArdHarald BergerManu ShuklaJesus Torres-GarciaCarolin A. MüllerConrad A. NieduszynskiRobin C. AllshireNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Pin Tong Alison L. Pidoux Nicholas R. T. Toda Ryan Ard Harald Berger Manu Shukla Jesus Torres-Garcia Carolin A. Müller Conrad A. Nieduszynski Robin C. Allshire Interspecies conservation of organisation and function between nonhomologous regional centromeres |
description |
Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin. |
format |
article |
author |
Pin Tong Alison L. Pidoux Nicholas R. T. Toda Ryan Ard Harald Berger Manu Shukla Jesus Torres-Garcia Carolin A. Müller Conrad A. Nieduszynski Robin C. Allshire |
author_facet |
Pin Tong Alison L. Pidoux Nicholas R. T. Toda Ryan Ard Harald Berger Manu Shukla Jesus Torres-Garcia Carolin A. Müller Conrad A. Nieduszynski Robin C. Allshire |
author_sort |
Pin Tong |
title |
Interspecies conservation of organisation and function between nonhomologous regional centromeres |
title_short |
Interspecies conservation of organisation and function between nonhomologous regional centromeres |
title_full |
Interspecies conservation of organisation and function between nonhomologous regional centromeres |
title_fullStr |
Interspecies conservation of organisation and function between nonhomologous regional centromeres |
title_full_unstemmed |
Interspecies conservation of organisation and function between nonhomologous regional centromeres |
title_sort |
interspecies conservation of organisation and function between nonhomologous regional centromeres |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/2326eb1cb7ff4d129bd2996e9215ca50 |
work_keys_str_mv |
AT pintong interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT alisonlpidoux interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT nicholasrttoda interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT ryanard interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT haraldberger interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT manushukla interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT jesustorresgarcia interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT carolinamuller interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT conradanieduszynski interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres AT robincallshire interspeciesconservationoforganisationandfunctionbetweennonhomologousregionalcentromeres |
_version_ |
1718379928413536256 |