Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis

Abstract Instability and excessive use of the knee joint can cause osteoarthritis (OA). Reasonable exercise can enhance the stability of the knee joint and prevent and relieve the occurrence and development of OA. As a key switch for inflammation, P2X purinoceptor 7 (P2X7) has attracted much attenti...

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Bibliographic Details
Main Authors: Zihao Li, Ziyu Huang, He Zhang, Jinghan Lu, Yicheng Tian, Shang Piao, Zhiming Lin, Lunhao Bai
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/2326f46472e94e9985149fbe6b9ad09f
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