Moderate-intensity exercise alleviates pyroptosis by promoting autophagy in osteoarthritis via the P2X7/AMPK/mTOR axis

Abstract Instability and excessive use of the knee joint can cause osteoarthritis (OA). Reasonable exercise can enhance the stability of the knee joint and prevent and relieve the occurrence and development of OA. As a key switch for inflammation, P2X purinoceptor 7 (P2X7) has attracted much attenti...

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Autores principales: Zihao Li, Ziyu Huang, He Zhang, Jinghan Lu, Yicheng Tian, Shang Piao, Zhiming Lin, Lunhao Bai
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/2326f46472e94e9985149fbe6b9ad09f
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