Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

The molecular classification of endometroid ovarian carcinomas (EnOC) has not been established, preventing the development of stratified therapeutic approaches. Here the authors characterise the molecular landscape of EnOC by whole exome sequencing, identifying clinically distinct disease subtypes.

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Autores principales:	Robert L. Hollis, John P. Thomson, Barbara Stanley, Michael Churchman, Alison M. Meynert, Tzyvia Rye, Clare Bartos, Yasushi Iida, Ian Croy, Melanie Mackean, Fiona Nussey, Aikou Okamoto, Colin A. Semple, Charlie Gourley, C. Simon Herrington
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/232b42338ac04ca39f011da44d0890a8
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spelling	oai:doaj.org-article:232b42338ac04ca39f011da44d0890a82021-12-02T19:16:29ZMolecular stratification of endometrioid ovarian carcinoma predicts clinical outcome10.1038/s41467-020-18819-52041-1723https://doaj.org/article/232b42338ac04ca39f011da44d0890a82020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18819-5https://doaj.org/toc/2041-1723The molecular classification of endometroid ovarian carcinomas (EnOC) has not been established, preventing the development of stratified therapeutic approaches. Here the authors characterise the molecular landscape of EnOC by whole exome sequencing, identifying clinically distinct disease subtypes.Robert L. HollisJohn P. ThomsonBarbara StanleyMichael ChurchmanAlison M. MeynertTzyvia RyeClare BartosYasushi IidaIan CroyMelanie MackeanFiona NusseyAikou OkamotoColin A. SempleCharlie GourleyC. Simon HerringtonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert L. Hollis John P. Thomson Barbara Stanley Michael Churchman Alison M. Meynert Tzyvia Rye Clare Bartos Yasushi Iida Ian Croy Melanie Mackean Fiona Nussey Aikou Okamoto Colin A. Semple Charlie Gourley C. Simon Herrington Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
description	The molecular classification of endometroid ovarian carcinomas (EnOC) has not been established, preventing the development of stratified therapeutic approaches. Here the authors characterise the molecular landscape of EnOC by whole exome sequencing, identifying clinically distinct disease subtypes.
format	article
author	Robert L. Hollis John P. Thomson Barbara Stanley Michael Churchman Alison M. Meynert Tzyvia Rye Clare Bartos Yasushi Iida Ian Croy Melanie Mackean Fiona Nussey Aikou Okamoto Colin A. Semple Charlie Gourley C. Simon Herrington
author_facet	Robert L. Hollis John P. Thomson Barbara Stanley Michael Churchman Alison M. Meynert Tzyvia Rye Clare Bartos Yasushi Iida Ian Croy Melanie Mackean Fiona Nussey Aikou Okamoto Colin A. Semple Charlie Gourley C. Simon Herrington
author_sort	Robert L. Hollis
title	Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
title_short	Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
title_full	Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
title_fullStr	Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
title_full_unstemmed	Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
title_sort	molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/232b42338ac04ca39f011da44d0890a8
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Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

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