Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α
Abstract Drug resistance is a major hurdle for the effectiveness of tamoxifen (TAM) to provide clinical benefit. Therefore, it is essential to identify a sensitizer that could be used to improve TAM efficacy in treating TAM‐resistant breast cancer. Here, we investigated the ability of baicalein to r...
Enregistré dans:
Auteurs principaux: | Yan Chen, Jingyu Zhang, Minqin Zhang, Yuxuan Song, Yue Zhang, Shuangqin Fan, Shuang Ren, Lingyun Fu, Nenling Zhang, Hui Hui, Xiangchun Shen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Wiley
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/232d8d40bfeb4e3186ed0cd28bc06495 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Baicalein suppresses lipopolysaccharide-induced acute lung injury by regulating Drp1-dependent mitochondrial fission of macrophages
par: Cheng Jiang, et autres
Publié: (2022) -
Novel circular RNA circATRNL1 accelerates the osteosarcoma aerobic glycolysis through targeting miR-409-3p/LDHA
par: Quanbin Zhang, et autres
Publié: (2021) -
Antitumor effects of the small molecule DMAMCL in neuroblastoma via suppressing aerobic glycolysis and targeting PFKL
par: Simeng Zhang, et autres
Publié: (2021) -
NOX4-derived ROS-induced overexpression of FOXM1 regulates aerobic glycolysis in glioblastoma
par: Xiangsheng Su, et autres
Publié: (2021) -
Integrating network pharmacological and experimental models to investigate the therapeutic effects of baicalein in glaucoma
par: Jiawei Yang, et autres
Publié: (2021)