IL-13 from intraepithelial lymphocytes regulates tissue homeostasis and protects against carcinogenesis in the skin
Epidermal intraepithelial lymphocytes (IEL) produce IL-13, but the physiological role of this cytokine production is not clear. Here the authors show that IEL-production of IL-13 is a vital lymphoid stress surveillance mechanism driving crosstalk with epithelial cells to maintain tissue homeostasis...
Guardado en:
Autores principales: | Tim Dalessandri, Greg Crawford, Mark Hayes, Rocio Castro Seoane, Jessica Strid |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/2335273dce5f444c94c9bd1335d4930d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes
por: Alejandro J Brenes, et al.
Publicado: (2021) -
IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes
por: Olivia J. James, et al.
Publicado: (2021) -
Intestinal intraepithelial lymphocyte cytometric pattern is more accurate than subepithelial deposits of anti-tissue transglutaminase IgA for the diagnosis of celiac disease in lymphocytic enteritis.
por: Fernando Fernández-Bañares, et al.
Publicado: (2014) -
Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes
por: Casandra Panea, et al.
Publicado: (2021) -
FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis
por: Weiwei Liang, et al.
Publicado: (2020)