Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates
Cutaneous squamous cell of the skin is a common neoplasm that frequently arises from precancerous actinic keratoses. Here, the authors carry out genomic analysis on matched sets of human lesions and compare with those in ultraviolet treated mice and identify conserved drivers of tumour development.
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Nature Portfolio
2016
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oai:doaj.org-article:2337471e297249159e9e90238c07490c2021-12-02T16:56:45ZCross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates10.1038/ncomms126012041-1723https://doaj.org/article/2337471e297249159e9e90238c07490c2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12601https://doaj.org/toc/2041-1723Cutaneous squamous cell of the skin is a common neoplasm that frequently arises from precancerous actinic keratoses. Here, the authors carry out genomic analysis on matched sets of human lesions and compare with those in ultraviolet treated mice and identify conserved drivers of tumour development.Vida ChitsazzadehCristian CoarfaJennifer A. DrummondTri NguyenAaron JosephSuneel ChilukuriElizabeth CharpiotCharles H. AdelmannGrace ChingTran N. NguyenCourtney NicholasValencia D. ThomasMichael MigdenDeborah MacFarlaneErika ThompsonJianjun ShenYoko TakataKayla McNieceMaxim A. PolanskyHussein A. AbbasKimal RajapaksheAdam GowerAvrum SpiraKyle R. CovingtonWeimin XiaoPreethi GunaratneCurtis PickeringMitchell FrederickJeffrey N. MyersLi ShenHui YaoXiaoping SuRonald P. RapiniDavid A. WheelerErnest T. HawkElsa R. FloresKenneth Y. TsaiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Vida Chitsazzadeh Cristian Coarfa Jennifer A. Drummond Tri Nguyen Aaron Joseph Suneel Chilukuri Elizabeth Charpiot Charles H. Adelmann Grace Ching Tran N. Nguyen Courtney Nicholas Valencia D. Thomas Michael Migden Deborah MacFarlane Erika Thompson Jianjun Shen Yoko Takata Kayla McNiece Maxim A. Polansky Hussein A. Abbas Kimal Rajapakshe Adam Gower Avrum Spira Kyle R. Covington Weimin Xiao Preethi Gunaratne Curtis Pickering Mitchell Frederick Jeffrey N. Myers Li Shen Hui Yao Xiaoping Su Ronald P. Rapini David A. Wheeler Ernest T. Hawk Elsa R. Flores Kenneth Y. Tsai Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| description |
Cutaneous squamous cell of the skin is a common neoplasm that frequently arises from precancerous actinic keratoses. Here, the authors carry out genomic analysis on matched sets of human lesions and compare with those in ultraviolet treated mice and identify conserved drivers of tumour development. |
| format |
article |
| author |
Vida Chitsazzadeh Cristian Coarfa Jennifer A. Drummond Tri Nguyen Aaron Joseph Suneel Chilukuri Elizabeth Charpiot Charles H. Adelmann Grace Ching Tran N. Nguyen Courtney Nicholas Valencia D. Thomas Michael Migden Deborah MacFarlane Erika Thompson Jianjun Shen Yoko Takata Kayla McNiece Maxim A. Polansky Hussein A. Abbas Kimal Rajapakshe Adam Gower Avrum Spira Kyle R. Covington Weimin Xiao Preethi Gunaratne Curtis Pickering Mitchell Frederick Jeffrey N. Myers Li Shen Hui Yao Xiaoping Su Ronald P. Rapini David A. Wheeler Ernest T. Hawk Elsa R. Flores Kenneth Y. Tsai |
| author_facet |
Vida Chitsazzadeh Cristian Coarfa Jennifer A. Drummond Tri Nguyen Aaron Joseph Suneel Chilukuri Elizabeth Charpiot Charles H. Adelmann Grace Ching Tran N. Nguyen Courtney Nicholas Valencia D. Thomas Michael Migden Deborah MacFarlane Erika Thompson Jianjun Shen Yoko Takata Kayla McNiece Maxim A. Polansky Hussein A. Abbas Kimal Rajapakshe Adam Gower Avrum Spira Kyle R. Covington Weimin Xiao Preethi Gunaratne Curtis Pickering Mitchell Frederick Jeffrey N. Myers Li Shen Hui Yao Xiaoping Su Ronald P. Rapini David A. Wheeler Ernest T. Hawk Elsa R. Flores Kenneth Y. Tsai |
| author_sort |
Vida Chitsazzadeh |
| title |
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| title_short |
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| title_full |
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| title_fullStr |
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| title_full_unstemmed |
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| title_sort |
cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/2337471e297249159e9e90238c07490c |
| work_keys_str_mv |
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