High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites

Mapping RNA accessibility is valuable for identifying functional/regulatory RNA regions. Here the authors introduce INTERFACE, an intracellular method that quantifies antisense hybridization efficacy of any number of RNA regions simultaneously via a transcriptional elongation output, measurable via...

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Autores principales: Mia K. Mihailovic, Jorge Vazquez-Anderson, Yan Li, Victoria Fry, Praveen Vimalathas, Daniel Herrera, Richard A. Lease, Warren B. Powell, Lydia M. Contreras
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/23489d4076474f688e376a0c9e4c7578
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spelling oai:doaj.org-article:23489d4076474f688e376a0c9e4c75782021-12-02T16:49:54ZHigh-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites10.1038/s41467-018-06207-z2041-1723https://doaj.org/article/23489d4076474f688e376a0c9e4c75782018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06207-zhttps://doaj.org/toc/2041-1723Mapping RNA accessibility is valuable for identifying functional/regulatory RNA regions. Here the authors introduce INTERFACE, an intracellular method that quantifies antisense hybridization efficacy of any number of RNA regions simultaneously via a transcriptional elongation output, measurable via RNA-seqMia K. MihailovicJorge Vazquez-AndersonYan LiVictoria FryPraveen VimalathasDaniel HerreraRichard A. LeaseWarren B. PowellLydia M. ContrerasNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mia K. Mihailovic
Jorge Vazquez-Anderson
Yan Li
Victoria Fry
Praveen Vimalathas
Daniel Herrera
Richard A. Lease
Warren B. Powell
Lydia M. Contreras
High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites
description Mapping RNA accessibility is valuable for identifying functional/regulatory RNA regions. Here the authors introduce INTERFACE, an intracellular method that quantifies antisense hybridization efficacy of any number of RNA regions simultaneously via a transcriptional elongation output, measurable via RNA-seq
format article
author Mia K. Mihailovic
Jorge Vazquez-Anderson
Yan Li
Victoria Fry
Praveen Vimalathas
Daniel Herrera
Richard A. Lease
Warren B. Powell
Lydia M. Contreras
author_facet Mia K. Mihailovic
Jorge Vazquez-Anderson
Yan Li
Victoria Fry
Praveen Vimalathas
Daniel Herrera
Richard A. Lease
Warren B. Powell
Lydia M. Contreras
author_sort Mia K. Mihailovic
title High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites
title_short High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites
title_full High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites
title_fullStr High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites
title_full_unstemmed High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites
title_sort high-throughput in vivo mapping of rna accessible interfaces to identify functional srna binding sites
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/23489d4076474f688e376a0c9e4c7578
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