High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites

High-throughput in vivo mapping of RNA accessible interfaces to identify functional sRNA binding sites

Mapping RNA accessibility is valuable for identifying functional/regulatory RNA regions. Here the authors introduce INTERFACE, an intracellular method that quantifies antisense hybridization efficacy of any number of RNA regions simultaneously via a transcriptional elongation output, measurable via...

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Autores principales: Mia K. Mihailovic, Jorge Vazquez-Anderson, Yan Li, Victoria Fry, Praveen Vimalathas, Daniel Herrera, Richard A. Lease, Warren B. Powell, Lydia M. Contreras
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/23489d4076474f688e376a0c9e4c7578
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