Trib3 is developmentally and nutritionally regulated in the brain but is dispensable for spatial memory, fear conditioning and sensing of amino acid-imbalanced diet.

Tribbles homolog 3 (TRIB3) is a mammalian pseudokinase that is induced in neuronal cell cultures in response to cell death-inducing stresses, including neurotrophic factor deprivation. TRIB3 is an inhibitor of activating transcription factor 4 (ATF4), the central transcriptional regulator in the euk...

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Autores principales: Tiit Örd, Jürgen Innos, Kersti Lilleväli, Triin Tekko, Silva Sütt, Daima Örd, Sulev Kõks, Eero Vasar, Tõnis Örd
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/234f6bdc74d049a99bfd86292faa2231
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