Defining the genetic and evolutionary architecture of alternative splicing in response to infection

Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.

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Autores principales: Maxime Rotival, Hélène Quach, Lluis Quintana-Murci
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/235692f5446b45fb923b7d65dc982c57
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spelling oai:doaj.org-article:235692f5446b45fb923b7d65dc982c572021-12-02T15:35:50ZDefining the genetic and evolutionary architecture of alternative splicing in response to infection10.1038/s41467-019-09689-72041-1723https://doaj.org/article/235692f5446b45fb923b7d65dc982c572019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09689-7https://doaj.org/toc/2041-1723Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.Maxime RotivalHélène QuachLluis Quintana-MurciNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Maxime Rotival
Hélène Quach
Lluis Quintana-Murci
Defining the genetic and evolutionary architecture of alternative splicing in response to infection
description Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.
format article
author Maxime Rotival
Hélène Quach
Lluis Quintana-Murci
author_facet Maxime Rotival
Hélène Quach
Lluis Quintana-Murci
author_sort Maxime Rotival
title Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_short Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_full Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_fullStr Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_full_unstemmed Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_sort defining the genetic and evolutionary architecture of alternative splicing in response to infection
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/235692f5446b45fb923b7d65dc982c57
work_keys_str_mv AT maximerotival definingthegeneticandevolutionaryarchitectureofalternativesplicinginresponsetoinfection
AT helenequach definingthegeneticandevolutionaryarchitectureofalternativesplicinginresponsetoinfection
AT lluisquintanamurci definingthegeneticandevolutionaryarchitectureofalternativesplicinginresponsetoinfection
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