Defining the genetic and evolutionary architecture of alternative splicing in response to infection

Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.

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Detalles Bibliográficos
Autores principales:	Maxime Rotival, Hélène Quach, Lluis Quintana-Murci
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/235692f5446b45fb923b7d65dc982c57
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spelling	oai:doaj.org-article:235692f5446b45fb923b7d65dc982c572021-12-02T15:35:50ZDefining the genetic and evolutionary architecture of alternative splicing in response to infection10.1038/s41467-019-09689-72041-1723https://doaj.org/article/235692f5446b45fb923b7d65dc982c572019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09689-7https://doaj.org/toc/2041-1723Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.Maxime RotivalHélène QuachLluis Quintana-MurciNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maxime Rotival Hélène Quach Lluis Quintana-Murci Defining the genetic and evolutionary architecture of alternative splicing in response to infection
description	Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.
format	article
author	Maxime Rotival Hélène Quach Lluis Quintana-Murci
author_facet	Maxime Rotival Hélène Quach Lluis Quintana-Murci
author_sort	Maxime Rotival
title	Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_short	Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_full	Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_fullStr	Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_full_unstemmed	Defining the genetic and evolutionary architecture of alternative splicing in response to infection
title_sort	defining the genetic and evolutionary architecture of alternative splicing in response to infection
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/235692f5446b45fb923b7d65dc982c57
work_keys_str_mv	AT maximerotival definingthegeneticandevolutionaryarchitectureofalternativesplicinginresponsetoinfection AT helenequach definingthegeneticandevolutionaryarchitectureofalternativesplicinginresponsetoinfection AT lluisquintanamurci definingthegeneticandevolutionaryarchitectureofalternativesplicinginresponsetoinfection
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Defining the genetic and evolutionary architecture of alternative splicing in response to infection

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