Ets-2 Propagates IL-6 Trans-Signaling Mediated Osteoclast-Like Changes in Human Rheumatoid Arthritis Synovial Fibroblast
Rheumatoid arthritis synovial fibroblasts (RASFs) contribute to synovial inflammation and bone destruction by producing a pleiotropic cytokine interleukin-6 (IL-6). However, the molecular mechanisms through which IL-6 propels RASFs to contribute to bone loss are not fully understood. In the present...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/235e6e57e302480c915e68cbf27cff6c |
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