IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella

Cancer metastasis is one of the major causes of cancer related deaths and there is an urgent need to find more clinically effective metastasis targeting agents. Here, the authors show that Salmonella YB1 inhibits metastasis in multiple mouse models of cancer through a mechanism dependent on IFN-γ an...

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Autores principales:	Qiubin Lin, Li Rong, Xian Jia, Renhao Li, Bin Yu, Jingchu Hu, Xiao Luo, S. R. Badea, Chen Xu, Guofeng Fu, Kejiong Lai, Ming-chun Lee, Baozhong Zhang, Huarui Gong, Nan Zhou, Xiao Lei Chen, Shu-hai Lin, Guo Fu, Jian-Dong Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23602877f25040a79dc5d8fa00d14efc
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spelling	oai:doaj.org-article:23602877f25040a79dc5d8fa00d14efc2021-12-02T16:49:11ZIFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella10.1038/s41467-021-22755-32041-1723https://doaj.org/article/23602877f25040a79dc5d8fa00d14efc2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22755-3https://doaj.org/toc/2041-1723Cancer metastasis is one of the major causes of cancer related deaths and there is an urgent need to find more clinically effective metastasis targeting agents. Here, the authors show that Salmonella YB1 inhibits metastasis in multiple mouse models of cancer through a mechanism dependent on IFN-γ and NK cells.Qiubin LinLi RongXian JiaRenhao LiBin YuJingchu HuXiao LuoS. R. BadeaChen XuGuofeng FuKejiong LaiMing-chun LeeBaozhong ZhangHuarui GongNan ZhouXiao Lei ChenShu-hai LinGuo FuJian-Dong HuangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qiubin Lin Li Rong Xian Jia Renhao Li Bin Yu Jingchu Hu Xiao Luo S. R. Badea Chen Xu Guofeng Fu Kejiong Lai Ming-chun Lee Baozhong Zhang Huarui Gong Nan Zhou Xiao Lei Chen Shu-hai Lin Guo Fu Jian-Dong Huang IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
description	Cancer metastasis is one of the major causes of cancer related deaths and there is an urgent need to find more clinically effective metastasis targeting agents. Here, the authors show that Salmonella YB1 inhibits metastasis in multiple mouse models of cancer through a mechanism dependent on IFN-γ and NK cells.
format	article
author	Qiubin Lin Li Rong Xian Jia Renhao Li Bin Yu Jingchu Hu Xiao Luo S. R. Badea Chen Xu Guofeng Fu Kejiong Lai Ming-chun Lee Baozhong Zhang Huarui Gong Nan Zhou Xiao Lei Chen Shu-hai Lin Guo Fu Jian-Dong Huang
author_facet	Qiubin Lin Li Rong Xian Jia Renhao Li Bin Yu Jingchu Hu Xiao Luo S. R. Badea Chen Xu Guofeng Fu Kejiong Lai Ming-chun Lee Baozhong Zhang Huarui Gong Nan Zhou Xiao Lei Chen Shu-hai Lin Guo Fu Jian-Dong Huang
author_sort	Qiubin Lin
title	IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
title_short	IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
title_full	IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
title_fullStr	IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
title_full_unstemmed	IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
title_sort	ifn-γ-dependent nk cell activation is essential to metastasis suppression by engineered salmonella
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/23602877f25040a79dc5d8fa00d14efc
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IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella

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