Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review

Malnutrition among patients with chronic liver disease (CLD) is a common complication with significant prognostic implications for patients with liver cirrhosis. Micronutrient deficiency has been associated with an increased risk of hepatic decompensation and is an independent risk factor for mortal...

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Autores principales: Ashley Bloom, Stephen Bloom, Hannah Silva, Amanda J. Nicoll, Rohit Sawhney
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/236351b4dce74a6babc846da7b13ee61
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spelling oai:doaj.org-article:236351b4dce74a6babc846da7b13ee612021-11-18T04:46:09ZZinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review1665-268110.1016/j.aohep.2021.100549https://doaj.org/article/236351b4dce74a6babc846da7b13ee612021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1665268121002489https://doaj.org/toc/1665-2681Malnutrition among patients with chronic liver disease (CLD) is a common complication with significant prognostic implications for patients with liver cirrhosis. Micronutrient deficiency has been associated with an increased risk of hepatic decompensation and is an independent risk factor for mortality among cirrhotic patients. Micronutrient deficiencies in patients with CLD include zinc, vitamin A, vitamin D and selenium. This review article aims to evaluate the literature to date on the complications of zinc deficiency in patients with CLD. A management algorithm for zinc replacement has also been proposed.Ashley BloomStephen BloomHannah SilvaAmanda J. NicollRohit SawhneyElsevierarticleChronic liver diseaseMalnutritionZincSpecialties of internal medicineRC581-951ENAnnals of Hepatology, Vol 25, Iss , Pp 100549- (2021)
institution DOAJ
collection DOAJ
language EN
topic Chronic liver disease
Malnutrition
Zinc
Specialties of internal medicine
RC581-951
spellingShingle Chronic liver disease
Malnutrition
Zinc
Specialties of internal medicine
RC581-951
Ashley Bloom
Stephen Bloom
Hannah Silva
Amanda J. Nicoll
Rohit Sawhney
Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review
description Malnutrition among patients with chronic liver disease (CLD) is a common complication with significant prognostic implications for patients with liver cirrhosis. Micronutrient deficiency has been associated with an increased risk of hepatic decompensation and is an independent risk factor for mortality among cirrhotic patients. Micronutrient deficiencies in patients with CLD include zinc, vitamin A, vitamin D and selenium. This review article aims to evaluate the literature to date on the complications of zinc deficiency in patients with CLD. A management algorithm for zinc replacement has also been proposed.
format article
author Ashley Bloom
Stephen Bloom
Hannah Silva
Amanda J. Nicoll
Rohit Sawhney
author_facet Ashley Bloom
Stephen Bloom
Hannah Silva
Amanda J. Nicoll
Rohit Sawhney
author_sort Ashley Bloom
title Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review
title_short Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review
title_full Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review
title_fullStr Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review
title_full_unstemmed Zinc supplementation and its benefits in the management of chronic liver disease: An in-depth literature review
title_sort zinc supplementation and its benefits in the management of chronic liver disease: an in-depth literature review
publisher Elsevier
publishDate 2021
url https://doaj.org/article/236351b4dce74a6babc846da7b13ee61
work_keys_str_mv AT ashleybloom zincsupplementationanditsbenefitsinthemanagementofchronicliverdiseaseanindepthliteraturereview
AT stephenbloom zincsupplementationanditsbenefitsinthemanagementofchronicliverdiseaseanindepthliteraturereview
AT hannahsilva zincsupplementationanditsbenefitsinthemanagementofchronicliverdiseaseanindepthliteraturereview
AT amandajnicoll zincsupplementationanditsbenefitsinthemanagementofchronicliverdiseaseanindepthliteraturereview
AT rohitsawhney zincsupplementationanditsbenefitsinthemanagementofchronicliverdiseaseanindepthliteraturereview
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