Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
Jocelyn S Garland Department of Medicine, Queen's University, Kingston, ON, Canada Abstract: Chronic kidney disease (CKD) is defined by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative as the presence of reduced kidney function or kidney damage for a period of 3 mo...
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Dove Medical Press
2014
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oai:doaj.org-article:2365a795cad44f248f2a8419e7ad0dc82021-12-02T01:17:43ZElevated body mass index as a risk factor for chronic kidney disease: current perspectives1178-7007https://doaj.org/article/2365a795cad44f248f2a8419e7ad0dc82014-07-01T00:00:00Zhttp://www.dovepress.com/elevated-body-mass-index-as-a-risk-factor-for-chronic-kidney-disease-c-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Jocelyn S Garland Department of Medicine, Queen's University, Kingston, ON, Canada Abstract: Chronic kidney disease (CKD) is defined by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative as the presence of reduced kidney function or kidney damage for a period of 3 months or greater. Obesity is considered a risk factor for CKD development, but its precise role in contributing to CKD and end stage kidney disease is not fully elucidated. In this narrative review, the objectives are to describe the pathogenesis of CKD in obesity, including the impact of altered adipokine secretion in obesity and CKD, and to provide an overview of the clinical studies assessing the risk of obesity and CKD development. Keywords: obesity, chronic renal disease, adipokineGarlJSDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2014, Iss default, Pp 347-355 (2014) |
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Specialties of internal medicine RC581-951 |
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Specialties of internal medicine RC581-951 Garl JS Elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
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Jocelyn S Garland Department of Medicine, Queen's University, Kingston, ON, Canada Abstract: Chronic kidney disease (CKD) is defined by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative as the presence of reduced kidney function or kidney damage for a period of 3 months or greater. Obesity is considered a risk factor for CKD development, but its precise role in contributing to CKD and end stage kidney disease is not fully elucidated. In this narrative review, the objectives are to describe the pathogenesis of CKD in obesity, including the impact of altered adipokine secretion in obesity and CKD, and to provide an overview of the clinical studies assessing the risk of obesity and CKD development. Keywords: obesity, chronic renal disease, adipokine |
format |
article |
author |
Garl JS |
author_facet |
Garl JS |
author_sort |
Garl |
title |
Elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
title_short |
Elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
title_full |
Elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
title_fullStr |
Elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
title_full_unstemmed |
Elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
title_sort |
elevated body mass index as a risk factor for chronic kidney disease: current perspectives |
publisher |
Dove Medical Press |
publishDate |
2014 |
url |
https://doaj.org/article/2365a795cad44f248f2a8419e7ad0dc8 |
work_keys_str_mv |
AT garl elevatedbodymassindexasariskfactorforchronickidneydiseasecurrentperspectives AT js elevatedbodymassindexasariskfactorforchronickidneydiseasecurrentperspectives |
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