Elevated body mass index as a risk factor for chronic kidney disease: current perspectives

Jocelyn S Garland Department of Medicine, Queen's University, Kingston, ON, Canada Abstract: Chronic kidney disease (CKD) is defined by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative as the presence of reduced kidney function or kidney damage for a period of 3 mo...

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Autores principales: Garl, JS
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Lenguaje:EN
Publicado: Dove Medical Press 2014
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Acceso en línea:https://doaj.org/article/2365a795cad44f248f2a8419e7ad0dc8
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spelling oai:doaj.org-article:2365a795cad44f248f2a8419e7ad0dc82021-12-02T01:17:43ZElevated body mass index as a risk factor for chronic kidney disease: current perspectives1178-7007https://doaj.org/article/2365a795cad44f248f2a8419e7ad0dc82014-07-01T00:00:00Zhttp://www.dovepress.com/elevated-body-mass-index-as-a-risk-factor-for-chronic-kidney-disease-c-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007 Jocelyn S Garland Department of Medicine, Queen's University, Kingston, ON, Canada Abstract: Chronic kidney disease (CKD) is defined by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative as the presence of reduced kidney function or kidney damage for a period of 3 months or greater. Obesity is considered a risk factor for CKD development, but its precise role in contributing to CKD and end stage kidney disease is not fully elucidated. In this narrative review, the objectives are to describe the pathogenesis of CKD in obesity, including the impact of altered adipokine secretion in obesity and CKD, and to provide an overview of the clinical studies assessing the risk of obesity and CKD development. Keywords: obesity, chronic renal disease, adipokineGarlJSDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2014, Iss default, Pp 347-355 (2014)
institution DOAJ
collection DOAJ
language EN
topic Specialties of internal medicine
RC581-951
spellingShingle Specialties of internal medicine
RC581-951
Garl
JS
Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
description Jocelyn S Garland Department of Medicine, Queen's University, Kingston, ON, Canada Abstract: Chronic kidney disease (CKD) is defined by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative as the presence of reduced kidney function or kidney damage for a period of 3 months or greater. Obesity is considered a risk factor for CKD development, but its precise role in contributing to CKD and end stage kidney disease is not fully elucidated. In this narrative review, the objectives are to describe the pathogenesis of CKD in obesity, including the impact of altered adipokine secretion in obesity and CKD, and to provide an overview of the clinical studies assessing the risk of obesity and CKD development. Keywords: obesity, chronic renal disease, adipokine
format article
author Garl
JS
author_facet Garl
JS
author_sort Garl
title Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
title_short Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
title_full Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
title_fullStr Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
title_full_unstemmed Elevated body mass index as a risk factor for chronic kidney disease: current perspectives
title_sort elevated body mass index as a risk factor for chronic kidney disease: current perspectives
publisher Dove Medical Press
publishDate 2014
url https://doaj.org/article/2365a795cad44f248f2a8419e7ad0dc8
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