Epithelial tension in the second heart field promotes mouse heart tube elongation

Epithelial progenitor cell growth in the second heart field contributes to heart morphogenesis but how this is regulated at the tissue level is unclear. Here, the authors show that cell elongation, polarized actomyosin and nuclear YAP/TAZ drive epithelial growth and correlate with mechanical tension...

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Auteurs principaux:	Alexandre Francou, Christopher De Bono, Robert G. Kelly
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/23683da733794ab082b1c8be084e700b
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id	oai:doaj.org-article:23683da733794ab082b1c8be084e700b
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spelling	oai:doaj.org-article:23683da733794ab082b1c8be084e700b2021-12-02T17:06:17ZEpithelial tension in the second heart field promotes mouse heart tube elongation10.1038/ncomms147702041-1723https://doaj.org/article/23683da733794ab082b1c8be084e700b2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14770https://doaj.org/toc/2041-1723Epithelial progenitor cell growth in the second heart field contributes to heart morphogenesis but how this is regulated at the tissue level is unclear. Here, the authors show that cell elongation, polarized actomyosin and nuclear YAP/TAZ drive epithelial growth and correlate with mechanical tension.Alexandre FrancouChristopher De BonoRobert G. KellyNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alexandre Francou Christopher De Bono Robert G. Kelly Epithelial tension in the second heart field promotes mouse heart tube elongation
description	Epithelial progenitor cell growth in the second heart field contributes to heart morphogenesis but how this is regulated at the tissue level is unclear. Here, the authors show that cell elongation, polarized actomyosin and nuclear YAP/TAZ drive epithelial growth and correlate with mechanical tension.
format	article
author	Alexandre Francou Christopher De Bono Robert G. Kelly
author_facet	Alexandre Francou Christopher De Bono Robert G. Kelly
author_sort	Alexandre Francou
title	Epithelial tension in the second heart field promotes mouse heart tube elongation
title_short	Epithelial tension in the second heart field promotes mouse heart tube elongation
title_full	Epithelial tension in the second heart field promotes mouse heart tube elongation
title_fullStr	Epithelial tension in the second heart field promotes mouse heart tube elongation
title_full_unstemmed	Epithelial tension in the second heart field promotes mouse heart tube elongation
title_sort	epithelial tension in the second heart field promotes mouse heart tube elongation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/23683da733794ab082b1c8be084e700b
work_keys_str_mv	AT alexandrefrancou epithelialtensioninthesecondheartfieldpromotesmousehearttubeelongation AT christopherdebono epithelialtensioninthesecondheartfieldpromotesmousehearttubeelongation AT robertgkelly epithelialtensioninthesecondheartfieldpromotesmousehearttubeelongation
_version_	1718381662455201792

Epithelial tension in the second heart field promotes mouse heart tube elongation

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