The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey

Abstract Background Non-communicable diseases (NCDs) are an increasing global concern, with morbidity and mortality largely occurring in low- and middle-income settings. We established the prospective Rural Uganda Non-Communicable Disease (RUNCD) cohort to longitudinally characterize the NCD prevale...

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Autores principales:	Trishul Siddharthan, Robert Kalyesubula, Brooks Morgan, Theresa Ermer, Tracy L. Rabin, Alex Kayongo, Richard Munana, Nora Anton, Katharina Kast, Elke Schaeffner, Bruce Kirenga, Felix Knauf, Rural Uganda Non Communicable Disease Study Investigators
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Non-communicable diseases Rural Low- and middle-income countries Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/2368f776eff446558226970a6c26f034
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spelling	oai:doaj.org-article:2368f776eff446558226970a6c26f0342021-11-14T12:14:55ZThe rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey10.1186/s12889-021-12123-71471-2458https://doaj.org/article/2368f776eff446558226970a6c26f0342021-11-01T00:00:00Zhttps://doi.org/10.1186/s12889-021-12123-7https://doaj.org/toc/1471-2458Abstract Background Non-communicable diseases (NCDs) are an increasing global concern, with morbidity and mortality largely occurring in low- and middle-income settings. We established the prospective Rural Uganda Non-Communicable Disease (RUNCD) cohort to longitudinally characterize the NCD prevalence, progression, and complications in rural Africa. Methods We conducted a population-based census for NCD research. We systematically enrolled adults in each household among three sub-counties of the larger Nakaseke Health district and collected baseline demographic, health status, and self-reported chronic disease information. We present our data on self-reported chronic disease, as stratified by age, sex, educational attainment, and sub-county. Results A total of 16,694 adults were surveyed with 10,563 (63%) respondents enrolled in the self-reported study. Average age was 37.8 years (SD = 16.5) and 45% (7481) were male. Among self-reported diseases, hypertension (HTN) was most prevalent (6.3%). 1.1% of participants reported a diagnosis of diabetes, 1.1% asthma, 0.7% COPD, and 0.4% kidney disease. 2.4% of the population described more than one NCD. Self-reported HTN was significantly higher in the peri-urban subcounty than in the other two rural sub-counties (p < 0.001); diagnoses for all other diseases did not differ significantly between sub-counties. Odds for self-reported HTN increased significantly with age (OR = 1.87 per 10 years of age, 95% CI 1.78–1.96). Male sex was associated with lower odds of reporting asthma (OR = 0.53, 95% CI 0.34–0.82) or HTN (OR = 0.31, 95% CI 0.26–0.40). Conclusions The RUNCD will establish one of the largest NCD patient cohorts in rural Africa. First analysis highlights the feasibility of systematically enrolling large numbers of adults living in a rural Ugandan district. In addition, our study demonstrates low levels of self-reported NCDs compared to the nation-wide established levels, emphasizing the need to better educate, characterize, and care for the majority of rural communities.Trishul SiddharthanRobert KalyesubulaBrooks MorganTheresa ErmerTracy L. RabinAlex KayongoRichard MunanaNora AntonKatharina KastElke SchaeffnerBruce KirengaFelix KnaufRural Uganda Non Communicable Disease Study InvestigatorsBMCarticleNon-communicable diseasesRuralLow- and middle-income countriesPublic aspects of medicineRA1-1270ENBMC Public Health, Vol 21, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Non-communicable diseases Rural Low- and middle-income countries Public aspects of medicine RA1-1270
spellingShingle	Non-communicable diseases Rural Low- and middle-income countries Public aspects of medicine RA1-1270 Trishul Siddharthan Robert Kalyesubula Brooks Morgan Theresa Ermer Tracy L. Rabin Alex Kayongo Richard Munana Nora Anton Katharina Kast Elke Schaeffner Bruce Kirenga Felix Knauf Rural Uganda Non Communicable Disease Study Investigators The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
description	Abstract Background Non-communicable diseases (NCDs) are an increasing global concern, with morbidity and mortality largely occurring in low- and middle-income settings. We established the prospective Rural Uganda Non-Communicable Disease (RUNCD) cohort to longitudinally characterize the NCD prevalence, progression, and complications in rural Africa. Methods We conducted a population-based census for NCD research. We systematically enrolled adults in each household among three sub-counties of the larger Nakaseke Health district and collected baseline demographic, health status, and self-reported chronic disease information. We present our data on self-reported chronic disease, as stratified by age, sex, educational attainment, and sub-county. Results A total of 16,694 adults were surveyed with 10,563 (63%) respondents enrolled in the self-reported study. Average age was 37.8 years (SD = 16.5) and 45% (7481) were male. Among self-reported diseases, hypertension (HTN) was most prevalent (6.3%). 1.1% of participants reported a diagnosis of diabetes, 1.1% asthma, 0.7% COPD, and 0.4% kidney disease. 2.4% of the population described more than one NCD. Self-reported HTN was significantly higher in the peri-urban subcounty than in the other two rural sub-counties (p < 0.001); diagnoses for all other diseases did not differ significantly between sub-counties. Odds for self-reported HTN increased significantly with age (OR = 1.87 per 10 years of age, 95% CI 1.78–1.96). Male sex was associated with lower odds of reporting asthma (OR = 0.53, 95% CI 0.34–0.82) or HTN (OR = 0.31, 95% CI 0.26–0.40). Conclusions The RUNCD will establish one of the largest NCD patient cohorts in rural Africa. First analysis highlights the feasibility of systematically enrolling large numbers of adults living in a rural Ugandan district. In addition, our study demonstrates low levels of self-reported NCDs compared to the nation-wide established levels, emphasizing the need to better educate, characterize, and care for the majority of rural communities.
format	article
author	Trishul Siddharthan Robert Kalyesubula Brooks Morgan Theresa Ermer Tracy L. Rabin Alex Kayongo Richard Munana Nora Anton Katharina Kast Elke Schaeffner Bruce Kirenga Felix Knauf Rural Uganda Non Communicable Disease Study Investigators
author_facet	Trishul Siddharthan Robert Kalyesubula Brooks Morgan Theresa Ermer Tracy L. Rabin Alex Kayongo Richard Munana Nora Anton Katharina Kast Elke Schaeffner Bruce Kirenga Felix Knauf Rural Uganda Non Communicable Disease Study Investigators
author_sort	Trishul Siddharthan
title	The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
title_short	The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
title_full	The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
title_fullStr	The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
title_full_unstemmed	The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey
title_sort	rural uganda non-communicable disease (runcd) study: prevalence and risk factors of self-reported ncds from a cross sectional survey
publisher	BMC
publishDate	2021
url	https://doaj.org/article/2368f776eff446558226970a6c26f034
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The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey

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