Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization

Podosomes are adhesive cytoskeletal structures found in several cell types, but whether or how they are interconnected is not known. Here the authors demonstrate mesoscale connectivity of podosome clusters by imaging directional flow patterns of podosome components vinculin, talin and F-actin.

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Autores principales:	Marjolein B. M. Meddens, Elvis Pandzic, Johan A. Slotman, Dominique Guillet, Ben Joosten, Svenja Mennens, Laurent M. Paardekooper, Adriaan B. Houtsmuller, Koen van den Dries, Paul W. Wiseman, Alessandra Cambi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2374938464cc43cd9e4d71359088ead0
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spelling	oai:doaj.org-article:2374938464cc43cd9e4d71359088ead02021-12-02T16:57:04ZActomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization10.1038/ncomms131272041-1723https://doaj.org/article/2374938464cc43cd9e4d71359088ead02016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13127https://doaj.org/toc/2041-1723Podosomes are adhesive cytoskeletal structures found in several cell types, but whether or how they are interconnected is not known. Here the authors demonstrate mesoscale connectivity of podosome clusters by imaging directional flow patterns of podosome components vinculin, talin and F-actin.Marjolein B. M. MeddensElvis PandzicJohan A. SlotmanDominique GuilletBen JoostenSvenja MennensLaurent M. PaardekooperAdriaan B. HoutsmullerKoen van den DriesPaul W. WisemanAlessandra CambiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marjolein B. M. Meddens Elvis Pandzic Johan A. Slotman Dominique Guillet Ben Joosten Svenja Mennens Laurent M. Paardekooper Adriaan B. Houtsmuller Koen van den Dries Paul W. Wiseman Alessandra Cambi Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
description	Podosomes are adhesive cytoskeletal structures found in several cell types, but whether or how they are interconnected is not known. Here the authors demonstrate mesoscale connectivity of podosome clusters by imaging directional flow patterns of podosome components vinculin, talin and F-actin.
format	article
author	Marjolein B. M. Meddens Elvis Pandzic Johan A. Slotman Dominique Guillet Ben Joosten Svenja Mennens Laurent M. Paardekooper Adriaan B. Houtsmuller Koen van den Dries Paul W. Wiseman Alessandra Cambi
author_facet	Marjolein B. M. Meddens Elvis Pandzic Johan A. Slotman Dominique Guillet Ben Joosten Svenja Mennens Laurent M. Paardekooper Adriaan B. Houtsmuller Koen van den Dries Paul W. Wiseman Alessandra Cambi
author_sort	Marjolein B. M. Meddens
title	Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
title_short	Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
title_full	Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
title_fullStr	Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
title_full_unstemmed	Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
title_sort	actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/2374938464cc43cd9e4d71359088ead0
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Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization

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