Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization

Podosomes are adhesive cytoskeletal structures found in several cell types, but whether or how they are interconnected is not known. Here the authors demonstrate mesoscale connectivity of podosome clusters by imaging directional flow patterns of podosome components vinculin, talin and F-actin.

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Autores principales: Marjolein B. M. Meddens, Elvis Pandzic, Johan A. Slotman, Dominique Guillet, Ben Joosten, Svenja Mennens, Laurent M. Paardekooper, Adriaan B. Houtsmuller, Koen van den Dries, Paul W. Wiseman, Alessandra Cambi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/2374938464cc43cd9e4d71359088ead0
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