SAPHO Syndrome: An Unusual Cause of Dysphagia

Case Presentation: This case describes a 51-year-old male who presented to the emergency department with a complaint of two weeks of progressively worsening dysphagia as well as the emergence of superficial fluid collections on the anterior chest and leg during the same period. Computed tomography s...

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Autores principales: Megan Hoffer, Michaela Salvo, Sonal Batra
Formato: article
Lenguaje:EN
Publicado: eScholarship Publishing, University of California 2021
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Acceso en línea:https://doaj.org/article/23883923254d47a09a13084abea150cd
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spelling oai:doaj.org-article:23883923254d47a09a13084abea150cd2021-11-23T20:02:52ZSAPHO Syndrome: An Unusual Cause of Dysphagia2474-252X10.5811/cpcem.2021.6.53001https://doaj.org/article/23883923254d47a09a13084abea150cd2021-11-01T00:00:00Zhttps://escholarship.org/uc/item/4tv9q218https://doaj.org/toc/2474-252XCase Presentation: This case describes a 51-year-old male who presented to the emergency department with a complaint of two weeks of progressively worsening dysphagia as well as the emergence of superficial fluid collections on the anterior chest and leg during the same period. Computed tomography showed retropharyngeal and paratracheal fluid collections with adjacent vertebral osteitis; however, biopsies were negative for any infectious or mycobacterial source, and instead showed chronic inflammatory changes. Discussion: Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare rheumatic disorder that presents with multifocal osteitis and sterile neutrophilia. SAPHO syndrome may be easily mistaken for a diffuse infectious process on initial evaluation and imaging; however, it is treated with anti-inflammatory medications, including non-steroidal anti-inflammatory drugs and corticosteroids. Although most patients achieve remission of symptoms with treatment, the location of the fluid collections and resultant bony destruction may be life-threatening if undiagnosed.Megan HofferMichaela SalvoSonal BatraeScholarship Publishing, University of CaliforniaarticleMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENClinical Practice and Cases in Emergency Medicine, Vol 5, Iss 4 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
spellingShingle Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Megan Hoffer
Michaela Salvo
Sonal Batra
SAPHO Syndrome: An Unusual Cause of Dysphagia
description Case Presentation: This case describes a 51-year-old male who presented to the emergency department with a complaint of two weeks of progressively worsening dysphagia as well as the emergence of superficial fluid collections on the anterior chest and leg during the same period. Computed tomography showed retropharyngeal and paratracheal fluid collections with adjacent vertebral osteitis; however, biopsies were negative for any infectious or mycobacterial source, and instead showed chronic inflammatory changes. Discussion: Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare rheumatic disorder that presents with multifocal osteitis and sterile neutrophilia. SAPHO syndrome may be easily mistaken for a diffuse infectious process on initial evaluation and imaging; however, it is treated with anti-inflammatory medications, including non-steroidal anti-inflammatory drugs and corticosteroids. Although most patients achieve remission of symptoms with treatment, the location of the fluid collections and resultant bony destruction may be life-threatening if undiagnosed.
format article
author Megan Hoffer
Michaela Salvo
Sonal Batra
author_facet Megan Hoffer
Michaela Salvo
Sonal Batra
author_sort Megan Hoffer
title SAPHO Syndrome: An Unusual Cause of Dysphagia
title_short SAPHO Syndrome: An Unusual Cause of Dysphagia
title_full SAPHO Syndrome: An Unusual Cause of Dysphagia
title_fullStr SAPHO Syndrome: An Unusual Cause of Dysphagia
title_full_unstemmed SAPHO Syndrome: An Unusual Cause of Dysphagia
title_sort sapho syndrome: an unusual cause of dysphagia
publisher eScholarship Publishing, University of California
publishDate 2021
url https://doaj.org/article/23883923254d47a09a13084abea150cd
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AT michaelasalvo saphosyndromeanunusualcauseofdysphagia
AT sonalbatra saphosyndromeanunusualcauseofdysphagia
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