Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response

Innate immune responses are essential in the control of flavivirus infection. Here, the authors provide evidence that the unfolded protein response and the pattern recognition receptor pathways synergize to orchestrate innate antiviral responses and cell intrinsic inhibition of viral replication, a...

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Autores principales:	Tea Carletti, Mohammad Khalid Zakaria, Valentina Faoro, Laura Reale, Yvette Kazungu, Danilo Licastro, Alessandro Marcello
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23926c2884b34717baa8f2d778cc3668
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spelling	oai:doaj.org-article:23926c2884b34717baa8f2d778cc36682021-12-02T17:01:34ZViral priming of cell intrinsic innate antiviral signaling by the unfolded protein response10.1038/s41467-019-11663-22041-1723https://doaj.org/article/23926c2884b34717baa8f2d778cc36682019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11663-2https://doaj.org/toc/2041-1723Innate immune responses are essential in the control of flavivirus infection. Here, the authors provide evidence that the unfolded protein response and the pattern recognition receptor pathways synergize to orchestrate innate antiviral responses and cell intrinsic inhibition of viral replication, a process mediated by IRF3.Tea CarlettiMohammad Khalid ZakariaValentina FaoroLaura RealeYvette KazunguDanilo LicastroAlessandro MarcelloNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tea Carletti Mohammad Khalid Zakaria Valentina Faoro Laura Reale Yvette Kazungu Danilo Licastro Alessandro Marcello Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
description	Innate immune responses are essential in the control of flavivirus infection. Here, the authors provide evidence that the unfolded protein response and the pattern recognition receptor pathways synergize to orchestrate innate antiviral responses and cell intrinsic inhibition of viral replication, a process mediated by IRF3.
format	article
author	Tea Carletti Mohammad Khalid Zakaria Valentina Faoro Laura Reale Yvette Kazungu Danilo Licastro Alessandro Marcello
author_facet	Tea Carletti Mohammad Khalid Zakaria Valentina Faoro Laura Reale Yvette Kazungu Danilo Licastro Alessandro Marcello
author_sort	Tea Carletti
title	Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
title_short	Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
title_full	Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
title_fullStr	Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
title_full_unstemmed	Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
title_sort	viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/23926c2884b34717baa8f2d778cc3668
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Viral priming of cell intrinsic innate antiviral signaling by the unfolded protein response

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