The gut microbiome is required for full protection against acute arsenic toxicity in mouse models

It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.

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Detalles Bibliográficos
Autores principales: Michael Coryell, Mark McAlpine, Nicholas V. Pinkham, Timothy R. McDermott, Seth T. Walk
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/2395c159cf4f4511ac552e2d6467ef5a
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Sumario:It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.