The gut microbiome is required for full protection against acute arsenic toxicity in mouse models

It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.

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Autores principales:	Michael Coryell, Mark McAlpine, Nicholas V. Pinkham, Timothy R. McDermott, Seth T. Walk
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2395c159cf4f4511ac552e2d6467ef5a
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spelling	oai:doaj.org-article:2395c159cf4f4511ac552e2d6467ef5a2021-12-02T17:31:57ZThe gut microbiome is required for full protection against acute arsenic toxicity in mouse models10.1038/s41467-018-07803-92041-1723https://doaj.org/article/2395c159cf4f4511ac552e2d6467ef5a2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07803-9https://doaj.org/toc/2041-1723It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.Michael CoryellMark McAlpineNicholas V. PinkhamTimothy R. McDermottSeth T. WalkNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michael Coryell Mark McAlpine Nicholas V. Pinkham Timothy R. McDermott Seth T. Walk The gut microbiome is required for full protection against acute arsenic toxicity in mouse models
description	It is unclear whether the gut microbiome can mitigate or exacerbate arsenic toxicity. Here, Coryell et al. show that the human gut microbiome protects mice from arsenic-induced mortality, with protection levels correlating with the relative abundance of the human commensal Faecalibacterium.
format	article
author	Michael Coryell Mark McAlpine Nicholas V. Pinkham Timothy R. McDermott Seth T. Walk
author_facet	Michael Coryell Mark McAlpine Nicholas V. Pinkham Timothy R. McDermott Seth T. Walk
author_sort	Michael Coryell
title	The gut microbiome is required for full protection against acute arsenic toxicity in mouse models
title_short	The gut microbiome is required for full protection against acute arsenic toxicity in mouse models
title_full	The gut microbiome is required for full protection against acute arsenic toxicity in mouse models
title_fullStr	The gut microbiome is required for full protection against acute arsenic toxicity in mouse models
title_full_unstemmed	The gut microbiome is required for full protection against acute arsenic toxicity in mouse models
title_sort	gut microbiome is required for full protection against acute arsenic toxicity in mouse models
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2395c159cf4f4511ac552e2d6467ef5a
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The gut microbiome is required for full protection against acute arsenic toxicity in mouse models

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