Multiplexed imaging of nucleome architectures in single cells of mammalian tissue

The three-dimensional architecture of the genome affects genomic functions. Here, the authors developed Multiplexed Imaging of Nucleome Architectures to measure multiscale chromatin folding, RNA profiles, and associations of numerous genomic regions with nuclear lamina and nucleoli in the same, sing...

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Autores principales:	Miao Liu, Yanfang Lu, Bing Yang, Yanbo Chen, Jonathan S. D. Radda, Mengwei Hu, Samuel G. Katz, Siyuan Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23a002745d5b4796868be007bae1e134
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spelling	oai:doaj.org-article:23a002745d5b4796868be007bae1e1342021-12-02T17:52:20ZMultiplexed imaging of nucleome architectures in single cells of mammalian tissue10.1038/s41467-020-16732-52041-1723https://doaj.org/article/23a002745d5b4796868be007bae1e1342020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16732-5https://doaj.org/toc/2041-1723The three-dimensional architecture of the genome affects genomic functions. Here, the authors developed Multiplexed Imaging of Nucleome Architectures to measure multiscale chromatin folding, RNA profiles, and associations of numerous genomic regions with nuclear lamina and nucleoli in the same, single cells in heterogeneous tissue.Miao LiuYanfang LuBing YangYanbo ChenJonathan S. D. RaddaMengwei HuSamuel G. KatzSiyuan WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miao Liu Yanfang Lu Bing Yang Yanbo Chen Jonathan S. D. Radda Mengwei Hu Samuel G. Katz Siyuan Wang Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
description	The three-dimensional architecture of the genome affects genomic functions. Here, the authors developed Multiplexed Imaging of Nucleome Architectures to measure multiscale chromatin folding, RNA profiles, and associations of numerous genomic regions with nuclear lamina and nucleoli in the same, single cells in heterogeneous tissue.
format	article
author	Miao Liu Yanfang Lu Bing Yang Yanbo Chen Jonathan S. D. Radda Mengwei Hu Samuel G. Katz Siyuan Wang
author_facet	Miao Liu Yanfang Lu Bing Yang Yanbo Chen Jonathan S. D. Radda Mengwei Hu Samuel G. Katz Siyuan Wang
author_sort	Miao Liu
title	Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
title_short	Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
title_full	Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
title_fullStr	Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
title_full_unstemmed	Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
title_sort	multiplexed imaging of nucleome architectures in single cells of mammalian tissue
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/23a002745d5b4796868be007bae1e134
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Multiplexed imaging of nucleome architectures in single cells of mammalian tissue

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