Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells.

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells.

Respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infection in children worldwide. Sirtuin 1 (SIRT1), a NAD+ dependent deacetylase, has been associated with induction of autophagy, reprogramming cellular metabolism, and regulating immune mediators. In this study, we inv...

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Autores principales: Srikanth Elesela, Susan B Morris, Samanthi Narayanan, Surinder Kumar, David B Lombard, Nicholas W Lukacs
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2020
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/23a18838d5664fb290b5aa945c0eccf1
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