THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO

Background: Norovirus has become a major cause of severe outbreaks of gastroenteritis since the discovery of the rotavirus vaccine, with the main symptom being diarrhea. Until now, research on the epidemiological analysis of norovirus has not been carried out at Regional Public Hospital (RSUD) Dr. S...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Alpha Fardah Athiyyah, Sofia Wardhani, Andy Darma, Reza Gunadi Ranuh, Dadik Raharjo, Toshiro Shirakawa, Subijanto Marto Sudarmo
Formato:	article
Lenguaje:	EN ID
Publicado:	Universitas Airlangga 2020
Materias:	diarrhea in children gastroenteritis clinical epidemiology norovirus infection enzyme immunoassay Public aspects of medicine RA1-1270 Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/23ac0a9eb12c4d95a3f625d3f0d760fb
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:23ac0a9eb12c4d95a3f625d3f0d760fb
record_format	dspace
spelling	oai:doaj.org-article:23ac0a9eb12c4d95a3f625d3f0d760fb2021-12-02T11:00:21ZTHE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO2301-71712541-092X10.20473/jbe.V8I32020.200-207https://doaj.org/article/23ac0a9eb12c4d95a3f625d3f0d760fb2020-09-01T00:00:00Zhttps://e-journal.unair.ac.id/JBE/article/view/14080https://doaj.org/toc/2301-7171https://doaj.org/toc/2541-092XBackground: Norovirus has become a major cause of severe outbreaks of gastroenteritis since the discovery of the rotavirus vaccine, with the main symptom being diarrhea. Until now, research on the epidemiological analysis of norovirus has not been carried out at Regional Public Hospital (RSUD) Dr. Soetomo, Surabaya. Purpose: This study aims to provide clinical epidemiology data and an analysis of norovirus infections in children with diarrhea at Regional Public Hospital (RSUD) Dr. Soetomo, Surabaya, Indonesia, including the prevalence of norovirus infection in each age group and sex, its clinical appearance, and its seasonal variation. Methods: A cross-sectional study was conducted in children aged 1–60 months hospitalized for diarrhea in RSUD Dr. Soetomo between April 2013 and March 2014. Identification of the virus in the stool was done by norovirus enzyme immunoassay Quick NaviTM Noro2. The proportion, age, sex, clinical symptoms, and patterns of the norovirus seasonal data were calculated. Results: Norovirus was detected in 64 samples (19%) of the 340 stool samples, with a mean patient age of 11.75 months; it was mostly found in patients less than 24 months of age (95%), and 64% were male. The monthly pattern of norovirus infection was mostly found in November, followed by May and April. The clinical symptoms were fever (72%), vomiting (66%), bloating (59%), abdominal cramps (34%), perianal inflammation (27%), abdominal distension (16%), and seizures (8%). Conclusion: The prevalence of norovirus was found to be high in patients with diarrhea aged 1–60 months hospitalized in RSUD Dr. Soetomo, with a proportion of 19%. Further research is needed to determine the severity of norovirus infection.Alpha Fardah AthiyyahSofia WardhaniAndy DarmaReza Gunadi RanuhDadik RaharjoToshiro ShirakawaSubijanto Marto SudarmoUniversitas Airlanggaarticlediarrhea in childrengastroenteritisclinical epidemiologynorovirus infectionenzyme immunoassayPublic aspects of medicineRA1-1270Infectious and parasitic diseasesRC109-216ENIDJurnal Berkala Epidemiologi, Vol 8, Iss 3, Pp 200-207 (2020)
institution	DOAJ
collection	DOAJ
language	EN ID
topic	diarrhea in children gastroenteritis clinical epidemiology norovirus infection enzyme immunoassay Public aspects of medicine RA1-1270 Infectious and parasitic diseases RC109-216
spellingShingle	diarrhea in children gastroenteritis clinical epidemiology norovirus infection enzyme immunoassay Public aspects of medicine RA1-1270 Infectious and parasitic diseases RC109-216 Alpha Fardah Athiyyah Sofia Wardhani Andy Darma Reza Gunadi Ranuh Dadik Raharjo Toshiro Shirakawa Subijanto Marto Sudarmo THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO
description	Background: Norovirus has become a major cause of severe outbreaks of gastroenteritis since the discovery of the rotavirus vaccine, with the main symptom being diarrhea. Until now, research on the epidemiological analysis of norovirus has not been carried out at Regional Public Hospital (RSUD) Dr. Soetomo, Surabaya. Purpose: This study aims to provide clinical epidemiology data and an analysis of norovirus infections in children with diarrhea at Regional Public Hospital (RSUD) Dr. Soetomo, Surabaya, Indonesia, including the prevalence of norovirus infection in each age group and sex, its clinical appearance, and its seasonal variation. Methods: A cross-sectional study was conducted in children aged 1–60 months hospitalized for diarrhea in RSUD Dr. Soetomo between April 2013 and March 2014. Identification of the virus in the stool was done by norovirus enzyme immunoassay Quick NaviTM Noro2. The proportion, age, sex, clinical symptoms, and patterns of the norovirus seasonal data were calculated. Results: Norovirus was detected in 64 samples (19%) of the 340 stool samples, with a mean patient age of 11.75 months; it was mostly found in patients less than 24 months of age (95%), and 64% were male. The monthly pattern of norovirus infection was mostly found in November, followed by May and April. The clinical symptoms were fever (72%), vomiting (66%), bloating (59%), abdominal cramps (34%), perianal inflammation (27%), abdominal distension (16%), and seizures (8%). Conclusion: The prevalence of norovirus was found to be high in patients with diarrhea aged 1–60 months hospitalized in RSUD Dr. Soetomo, with a proportion of 19%. Further research is needed to determine the severity of norovirus infection.
format	article
author	Alpha Fardah Athiyyah Sofia Wardhani Andy Darma Reza Gunadi Ranuh Dadik Raharjo Toshiro Shirakawa Subijanto Marto Sudarmo
author_facet	Alpha Fardah Athiyyah Sofia Wardhani Andy Darma Reza Gunadi Ranuh Dadik Raharjo Toshiro Shirakawa Subijanto Marto Sudarmo
author_sort	Alpha Fardah Athiyyah
title	THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO
title_short	THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO
title_full	THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO
title_fullStr	THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO
title_full_unstemmed	THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO
title_sort	clinical epidemiology of norovirus infection in children with diarrhea at regional public hospital dr.soetomo
publisher	Universitas Airlangga
publishDate	2020
url	https://doaj.org/article/23ac0a9eb12c4d95a3f625d3f0d760fb
work_keys_str_mv	AT alphafardahathiyyah theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT sofiawardhani theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT andydarma theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT rezagunadiranuh theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT dadikraharjo theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT toshiroshirakawa theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT subijantomartosudarmo theclinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT alphafardahathiyyah clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT sofiawardhani clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT andydarma clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT rezagunadiranuh clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT dadikraharjo clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT toshiroshirakawa clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo AT subijantomartosudarmo clinicalepidemiologyofnorovirusinfectioninchildrenwithdiarrheaatregionalpublichospitaldrsoetomo
_version_	1718396342194143232

THE CLINICAL EPIDEMIOLOGY OF NOROVIRUS INFECTION IN CHILDREN WITH DIARRHEA AT REGIONAL PUBLIC HOSPITAL DR.SOETOMO

Ejemplares similares