Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions

The tasks of the cytoskeleton depend on the fine-tuned interplay between the three filamentous components: actin filaments, microtubules, and intermediate filaments. Here, the authors show in a reconstituted in vitro system that vimentin intermediate filaments stabilize microtubules against depolyme...

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Autores principales:	Laura Schaedel, Charlotta Lorenz, Anna V. Schepers, Stefan Klumpp, Sarah Köster
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23b2e8f87d2c4f0b81118609b696d3b4
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spelling	oai:doaj.org-article:23b2e8f87d2c4f0b81118609b696d3b42021-12-02T16:04:34ZVimentin intermediate filaments stabilize dynamic microtubules by direct interactions10.1038/s41467-021-23523-z2041-1723https://doaj.org/article/23b2e8f87d2c4f0b81118609b696d3b42021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23523-zhttps://doaj.org/toc/2041-1723The tasks of the cytoskeleton depend on the fine-tuned interplay between the three filamentous components: actin filaments, microtubules, and intermediate filaments. Here, the authors show in a reconstituted in vitro system that vimentin intermediate filaments stabilize microtubules against depolymerization and support microtubule rescue by direct interactions.Laura SchaedelCharlotta LorenzAnna V. SchepersStefan KlumppSarah KösterNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laura Schaedel Charlotta Lorenz Anna V. Schepers Stefan Klumpp Sarah Köster Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
description	The tasks of the cytoskeleton depend on the fine-tuned interplay between the three filamentous components: actin filaments, microtubules, and intermediate filaments. Here, the authors show in a reconstituted in vitro system that vimentin intermediate filaments stabilize microtubules against depolymerization and support microtubule rescue by direct interactions.
format	article
author	Laura Schaedel Charlotta Lorenz Anna V. Schepers Stefan Klumpp Sarah Köster
author_facet	Laura Schaedel Charlotta Lorenz Anna V. Schepers Stefan Klumpp Sarah Köster
author_sort	Laura Schaedel
title	Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
title_short	Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
title_full	Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
title_fullStr	Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
title_full_unstemmed	Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
title_sort	vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/23b2e8f87d2c4f0b81118609b696d3b4
work_keys_str_mv	AT lauraschaedel vimentinintermediatefilamentsstabilizedynamicmicrotubulesbydirectinteractions AT charlottalorenz vimentinintermediatefilamentsstabilizedynamicmicrotubulesbydirectinteractions AT annavschepers vimentinintermediatefilamentsstabilizedynamicmicrotubulesbydirectinteractions AT stefanklumpp vimentinintermediatefilamentsstabilizedynamicmicrotubulesbydirectinteractions AT sarahkoster vimentinintermediatefilamentsstabilizedynamicmicrotubulesbydirectinteractions
_version_	1718385196468797440

Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions

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