Nanocarriers for Inner Ear Disease Therapy

Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects. Currently, traditional drug delivery systems exhibit the potential to be us...

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Autores principales: Xiaoxiang Xu, Jianwei Zheng, Yanze He, Kun Lin, Shuang Li, Ya Zhang, Peng Song, Yuye Zhou, Xiong Chen
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/23b4ef78cb484009af99d352434b29b0
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spelling oai:doaj.org-article:23b4ef78cb484009af99d352434b29b02021-12-03T04:56:38ZNanocarriers for Inner Ear Disease Therapy1662-510210.3389/fncel.2021.791573https://doaj.org/article/23b4ef78cb484009af99d352434b29b02021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fncel.2021.791573/fullhttps://doaj.org/toc/1662-5102Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects. Currently, traditional drug delivery systems exhibit the potential to be used for inner ear disease therapy, but there are still some drawbacks. As nanotechnology is developing these years, one of the solutions is to develop nanoparticle-based delivery systems for inner ear disease therapy. Various nanoparticles, such as soft material and inorganic-based nanoparticles, have been designed, tested, and showed controlled delivery of drugs, improved targeting property to specific cells, and reduced systemic side effects. In this review, we summarized recent progress in nanocarriers for inner ear disease therapy. This review provides useful information on developing promising nanocarriers for the efficient treatment of inner ear diseases and for further clinical applications for inner ear disease therapy.Xiaoxiang XuXiaoxiang XuJianwei ZhengYanze HeKun LinShuang LiYa ZhangPeng SongYuye ZhouYuye ZhouXiong ChenFrontiers Media S.A.articlenanocarrierdrug delivery systeminner ear disease therapysoft material nanoparticleinorganic nanoparticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENFrontiers in Cellular Neuroscience, Vol 15 (2021)
institution DOAJ
collection DOAJ
language EN
topic nanocarrier
drug delivery system
inner ear disease therapy
soft material nanoparticle
inorganic nanoparticle
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
spellingShingle nanocarrier
drug delivery system
inner ear disease therapy
soft material nanoparticle
inorganic nanoparticle
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Xiaoxiang Xu
Xiaoxiang Xu
Jianwei Zheng
Yanze He
Kun Lin
Shuang Li
Ya Zhang
Peng Song
Yuye Zhou
Yuye Zhou
Xiong Chen
Nanocarriers for Inner Ear Disease Therapy
description Hearing loss is a common disease due to sensory loss caused by the diseases in the inner ear. The development of delivery systems for inner ear disease therapy is important to achieve high efficiency and reduce side effects. Currently, traditional drug delivery systems exhibit the potential to be used for inner ear disease therapy, but there are still some drawbacks. As nanotechnology is developing these years, one of the solutions is to develop nanoparticle-based delivery systems for inner ear disease therapy. Various nanoparticles, such as soft material and inorganic-based nanoparticles, have been designed, tested, and showed controlled delivery of drugs, improved targeting property to specific cells, and reduced systemic side effects. In this review, we summarized recent progress in nanocarriers for inner ear disease therapy. This review provides useful information on developing promising nanocarriers for the efficient treatment of inner ear diseases and for further clinical applications for inner ear disease therapy.
format article
author Xiaoxiang Xu
Xiaoxiang Xu
Jianwei Zheng
Yanze He
Kun Lin
Shuang Li
Ya Zhang
Peng Song
Yuye Zhou
Yuye Zhou
Xiong Chen
author_facet Xiaoxiang Xu
Xiaoxiang Xu
Jianwei Zheng
Yanze He
Kun Lin
Shuang Li
Ya Zhang
Peng Song
Yuye Zhou
Yuye Zhou
Xiong Chen
author_sort Xiaoxiang Xu
title Nanocarriers for Inner Ear Disease Therapy
title_short Nanocarriers for Inner Ear Disease Therapy
title_full Nanocarriers for Inner Ear Disease Therapy
title_fullStr Nanocarriers for Inner Ear Disease Therapy
title_full_unstemmed Nanocarriers for Inner Ear Disease Therapy
title_sort nanocarriers for inner ear disease therapy
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/23b4ef78cb484009af99d352434b29b0
work_keys_str_mv AT xiaoxiangxu nanocarriersforinnereardiseasetherapy
AT xiaoxiangxu nanocarriersforinnereardiseasetherapy
AT jianweizheng nanocarriersforinnereardiseasetherapy
AT yanzehe nanocarriersforinnereardiseasetherapy
AT kunlin nanocarriersforinnereardiseasetherapy
AT shuangli nanocarriersforinnereardiseasetherapy
AT yazhang nanocarriersforinnereardiseasetherapy
AT pengsong nanocarriersforinnereardiseasetherapy
AT yuyezhou nanocarriersforinnereardiseasetherapy
AT yuyezhou nanocarriersforinnereardiseasetherapy
AT xiongchen nanocarriersforinnereardiseasetherapy
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