GATA3 maintains the quiescent state of cochlear supporting cells by regulating p27kip1

GATA3 maintains the quiescent state of cochlear supporting cells by regulating p27kip1

Abstract Haplo-insufficiency of the GATA3 gene causes hypoparathyroidism, sensorineural hearing loss, and renal disease (HDR) syndrome. Previous studies have shown that Gata3 is required for the development of the prosensory domain and spiral ganglion neurons (SGNs) of the mouse cochlea during embry...

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Autores principales: Jiadong Xu, Dongliang Yu, Xuhui Dong, Xiaoling Xie, Mei Xu, Luming Guo, Liang Huang, Qi Tang, Lin Gan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/23c3e3f6c1b441e0bcc5c88826456c7e
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