Revealing the suppressive role of protein kinase C delta and p38 mitogen-activated protein kinase (MAPK)/NF-κB axis associates with lenvatinib-inhibited progression in hepatocellular carcinoma in vitro and in vivo
Nuclear factor-kappa B (NF-κB), an oncogenic transcription factor, modulates tumor formation and progression by inducing the expression of oncogenes involved in proliferation, survival, angiogenesis, and metastasis. Oral multikinase inhibitors, such as sorafenib, regorafenib, and lenvatinib have bee...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Elsevier
2022
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| Subjects: | |
| Online Access: | https://doaj.org/article/23c6c3bfdf354e649f144011c23f16be |
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