Par complex cluster formation mediated by phase separation

The evolutionarily conserved complex, the Par proteins, regulates cell polarity. Here, the authors show that in Drosophila neuroblasts, the Par complex exhibits liquid–liquid phase separation dependent on the cell cycle.

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Detalles Bibliográficos
Autores principales: Ziheng Liu, Ying Yang, Aihong Gu, Jiawen Xu, Ying Mao, Haojie Lu, Weiguo Hu, Qun-Ying Lei, Zhouhua Li, Mingjie Zhang, Yu Cai, Wenyu Wen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/23dbf619503b41d390a1459f50303a9b
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Sumario:The evolutionarily conserved complex, the Par proteins, regulates cell polarity. Here, the authors show that in Drosophila neuroblasts, the Par complex exhibits liquid–liquid phase separation dependent on the cell cycle.