Par complex cluster formation mediated by phase separation

The evolutionarily conserved complex, the Par proteins, regulates cell polarity. Here, the authors show that in Drosophila neuroblasts, the Par complex exhibits liquid–liquid phase separation dependent on the cell cycle.

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Autores principales:	Ziheng Liu, Ying Yang, Aihong Gu, Jiawen Xu, Ying Mao, Haojie Lu, Weiguo Hu, Qun-Ying Lei, Zhouhua Li, Mingjie Zhang, Yu Cai, Wenyu Wen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/23dbf619503b41d390a1459f50303a9b
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id	oai:doaj.org-article:23dbf619503b41d390a1459f50303a9b
record_format	dspace
spelling	oai:doaj.org-article:23dbf619503b41d390a1459f50303a9b2021-12-02T14:41:13ZPar complex cluster formation mediated by phase separation10.1038/s41467-020-16135-62041-1723https://doaj.org/article/23dbf619503b41d390a1459f50303a9b2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16135-6https://doaj.org/toc/2041-1723The evolutionarily conserved complex, the Par proteins, regulates cell polarity. Here, the authors show that in Drosophila neuroblasts, the Par complex exhibits liquid–liquid phase separation dependent on the cell cycle.Ziheng LiuYing YangAihong GuJiawen XuYing MaoHaojie LuWeiguo HuQun-Ying LeiZhouhua LiMingjie ZhangYu CaiWenyu WenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ziheng Liu Ying Yang Aihong Gu Jiawen Xu Ying Mao Haojie Lu Weiguo Hu Qun-Ying Lei Zhouhua Li Mingjie Zhang Yu Cai Wenyu Wen Par complex cluster formation mediated by phase separation
description	The evolutionarily conserved complex, the Par proteins, regulates cell polarity. Here, the authors show that in Drosophila neuroblasts, the Par complex exhibits liquid–liquid phase separation dependent on the cell cycle.
format	article
author	Ziheng Liu Ying Yang Aihong Gu Jiawen Xu Ying Mao Haojie Lu Weiguo Hu Qun-Ying Lei Zhouhua Li Mingjie Zhang Yu Cai Wenyu Wen
author_facet	Ziheng Liu Ying Yang Aihong Gu Jiawen Xu Ying Mao Haojie Lu Weiguo Hu Qun-Ying Lei Zhouhua Li Mingjie Zhang Yu Cai Wenyu Wen
author_sort	Ziheng Liu
title	Par complex cluster formation mediated by phase separation
title_short	Par complex cluster formation mediated by phase separation
title_full	Par complex cluster formation mediated by phase separation
title_fullStr	Par complex cluster formation mediated by phase separation
title_full_unstemmed	Par complex cluster formation mediated by phase separation
title_sort	par complex cluster formation mediated by phase separation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/23dbf619503b41d390a1459f50303a9b
work_keys_str_mv	AT zihengliu parcomplexclusterformationmediatedbyphaseseparation AT yingyang parcomplexclusterformationmediatedbyphaseseparation AT aihonggu parcomplexclusterformationmediatedbyphaseseparation AT jiawenxu parcomplexclusterformationmediatedbyphaseseparation AT yingmao parcomplexclusterformationmediatedbyphaseseparation AT haojielu parcomplexclusterformationmediatedbyphaseseparation AT weiguohu parcomplexclusterformationmediatedbyphaseseparation AT qunyinglei parcomplexclusterformationmediatedbyphaseseparation AT zhouhuali parcomplexclusterformationmediatedbyphaseseparation AT mingjiezhang parcomplexclusterformationmediatedbyphaseseparation AT yucai parcomplexclusterformationmediatedbyphaseseparation AT wenyuwen parcomplexclusterformationmediatedbyphaseseparation
_version_	1718389978547879936

Par complex cluster formation mediated by phase separation

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