The effect of intravitreal injections on dry eye, and proposed management strategies

Augustinus Laude,1–3 Jimmy WK Lim,1,2 Vishwanath Srinagesh,4 Louis Tong2,5–7 1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 2Singapore Eye Research Institute, 3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 4Krieger Eye Institu...

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Autores principales:	Laude A, Lim JWK, Srinagesh V, Tong L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Age-related macular degeneration (AMD) povidone-iodine toxicity ocular health chronic ophthalmic treatment Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/23e486a9f8e542aba69d8c748c58c022
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spelling	oai:doaj.org-article:23e486a9f8e542aba69d8c748c58c0222021-12-02T07:59:13ZThe effect of intravitreal injections on dry eye, and proposed management strategies1177-5483https://doaj.org/article/23e486a9f8e542aba69d8c748c58c0222017-08-01T00:00:00Zhttps://www.dovepress.com/the-effect-of-intravitreal-injections-on-dry-eye-and-proposed-manageme-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Augustinus Laude,1–3 Jimmy WK Lim,1,2 Vishwanath Srinagesh,4 Louis Tong2,5–7 1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 2Singapore Eye Research Institute, 3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 4Krieger Eye Institute, Baltimore, MD, USA; 5Singapore National Eye Centre, 6Duke NUS Medical School, 7Yong Loo Lin School of Medicine, National University of Singapore, Singapore Abstract: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents has become a commonly used treatment method for a number of ophthalmic conditions, including age-related macular degeneration. Although anti-VEGF therapy has shown promising results for many patients, there are several aspects of its application that have not been thoroughly investigated. One of these is the development and/or escalation of concurrent dry eye syndrome. Many patients undergoing treatment are already predisposed to dry eye disease due to their age and overall ocular health. As dry eye can have a substantial impact on quality of life, it has become increasingly apparent that the clinical signs and symptoms should be closely monitored and aggressively managed. This will allow for the optimization of patient comfort and visual potential. Here, we discuss the reasons why dry eye may develop during the course of repeated ocular anti-VEGF therapy, highlighting the key concerns about current practices and proposing possible solutions to improve the outcome for the patients. Keywords: age-related macular degeneration, povidone–iodine, toxicity, ocular health, chronic ophthalmic treatmentLaude ALim JWKSrinagesh VTong LDove Medical PressarticleAge-related macular degeneration (AMD)povidone-iodinetoxicityocular healthchronic ophthalmic treatmentOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 1491-1497 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Age-related macular degeneration (AMD) povidone-iodine toxicity ocular health chronic ophthalmic treatment Ophthalmology RE1-994
spellingShingle	Age-related macular degeneration (AMD) povidone-iodine toxicity ocular health chronic ophthalmic treatment Ophthalmology RE1-994 Laude A Lim JWK Srinagesh V Tong L The effect of intravitreal injections on dry eye, and proposed management strategies
description	Augustinus Laude,1–3 Jimmy WK Lim,1,2 Vishwanath Srinagesh,4 Louis Tong2,5–7 1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 2Singapore Eye Research Institute, 3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 4Krieger Eye Institute, Baltimore, MD, USA; 5Singapore National Eye Centre, 6Duke NUS Medical School, 7Yong Loo Lin School of Medicine, National University of Singapore, Singapore Abstract: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents has become a commonly used treatment method for a number of ophthalmic conditions, including age-related macular degeneration. Although anti-VEGF therapy has shown promising results for many patients, there are several aspects of its application that have not been thoroughly investigated. One of these is the development and/or escalation of concurrent dry eye syndrome. Many patients undergoing treatment are already predisposed to dry eye disease due to their age and overall ocular health. As dry eye can have a substantial impact on quality of life, it has become increasingly apparent that the clinical signs and symptoms should be closely monitored and aggressively managed. This will allow for the optimization of patient comfort and visual potential. Here, we discuss the reasons why dry eye may develop during the course of repeated ocular anti-VEGF therapy, highlighting the key concerns about current practices and proposing possible solutions to improve the outcome for the patients. Keywords: age-related macular degeneration, povidone–iodine, toxicity, ocular health, chronic ophthalmic treatment
format	article
author	Laude A Lim JWK Srinagesh V Tong L
author_facet	Laude A Lim JWK Srinagesh V Tong L
author_sort	Laude A
title	The effect of intravitreal injections on dry eye, and proposed management strategies
title_short	The effect of intravitreal injections on dry eye, and proposed management strategies
title_full	The effect of intravitreal injections on dry eye, and proposed management strategies
title_fullStr	The effect of intravitreal injections on dry eye, and proposed management strategies
title_full_unstemmed	The effect of intravitreal injections on dry eye, and proposed management strategies
title_sort	effect of intravitreal injections on dry eye, and proposed management strategies
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/23e486a9f8e542aba69d8c748c58c022
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The effect of intravitreal injections on dry eye, and proposed management strategies

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