The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.

<h4>Background</h4>MBD5 and MBD6 are two uncharacterized mammalian proteins that contain a putative Methyl-Binding Domain (MBD). In the proteins MBD1, MBD2, MBD4, and MeCP2, this domain allows the specific recognition of DNA containing methylated cytosine; as a consequence, the proteins...

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Autores principales: Sophie Laget, Michael Joulie, Florent Le Masson, Nobuhiro Sasai, Elisabeth Christians, Sriharsa Pradhan, Richard J Roberts, Pierre-Antoine Defossez
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/23e7c5a57b244ae4b24a4b6fb68b9666
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