The human proteins MBD5 and MBD6 associate with heterochromatin but they do not bind methylated DNA.
<h4>Background</h4>MBD5 and MBD6 are two uncharacterized mammalian proteins that contain a putative Methyl-Binding Domain (MBD). In the proteins MBD1, MBD2, MBD4, and MeCP2, this domain allows the specific recognition of DNA containing methylated cytosine; as a consequence, the proteins...
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Autores principales: | Sophie Laget, Michael Joulie, Florent Le Masson, Nobuhiro Sasai, Elisabeth Christians, Sriharsa Pradhan, Richard J Roberts, Pierre-Antoine Defossez |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/23e7c5a57b244ae4b24a4b6fb68b9666 |
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